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新生儿期高胆红素血症与特发性垂体功能减退症

Hyperbilirubinaemia and idiopathic hypopituitarism in the newborn period.

作者信息

Drop S L, Colle E, Guyda H J

出版信息

Acta Paediatr Scand. 1979 Mar;68(2):277-80. doi: 10.1111/j.1651-2227.1979.tb05003.x.

DOI:10.1111/j.1651-2227.1979.tb05003.x
PMID:419996
Abstract

Two infants with idiopathic panhypopituitarism presented with severe neonatal hypoglycaemia, hepatomegaly and hyperbilirubinaemia (direct and indirect). Abnormal liver function tests returned to normal over a 5--8 month period. The growth rate in the absence of detectable growth hormone was 50% of normal during the first 6 months. The effect of growth hormone on somatomedin levels and growth rate during the first year of life in one of the infants is described.

摘要

两名患有特发性全垂体功能减退症的婴儿出现严重的新生儿低血糖、肝肿大和高胆红素血症(直接胆红素和间接胆红素均升高)。肝功能检查异常在5至8个月的时间内恢复正常。在最初6个月中,在未检测到生长激素的情况下,生长速率为正常速率的50%。本文描述了生长激素对其中一名婴儿出生后第一年中生长介素水平和生长速率的影响。

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1
Hyperbilirubinaemia and idiopathic hypopituitarism in the newborn period.新生儿期高胆红素血症与特发性垂体功能减退症
Acta Paediatr Scand. 1979 Mar;68(2):277-80. doi: 10.1111/j.1651-2227.1979.tb05003.x.
2
Neonatal hyperbilirubinemia and hypoglycemia in congenital hypopituitarism.先天性垂体功能减退症中的新生儿高胆红素血症和低血糖症。
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[Hypoglycemia and cholestatic jaundice in congenital panhypopituitarism].先天性全垂体功能减退症中的低血糖和胆汁淤积性黄疸
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Congenital hypopituitarism and conjugated hyperbilirubinemia in two infants.两名婴儿的先天性垂体功能减退和结合性高胆红素血症。
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Liver dysfunction and hypoglycaemia as presentations of hypopituitarism in a child.肝功能障碍和低血糖症作为儿童垂体功能减退症的表现。
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Congenital hypopituitarism associated with neonatal hypoglycemia and microphallus: effect of GH therapy.
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J Perinatol. 2022 Jun;42(6):695-701. doi: 10.1038/s41372-022-01330-8. Epub 2022 Feb 10.
2
Cholestasis Reveals Severe Cortisol Deficiency in Neonatal Pituitary Stalk Interruption Syndrome.胆汁淤积揭示新生儿垂体柄中断综合征中严重的皮质醇缺乏
PLoS One. 2016 Feb 1;11(2):e0147750. doi: 10.1371/journal.pone.0147750. eCollection 2016.
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Diagnostic pitfalls in the assessment of congenital hypopituitarism.
先天性垂体功能减退症评估中的诊断陷阱。
J Endocrinol Invest. 2014 Dec;37(12):1201-9. doi: 10.1007/s40618-014-0139-9. Epub 2014 Aug 1.
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Dose Adjustments of Hydrocortisone and L-thyroxine in Hypopituitarism Associated with Cholestasis.垂体功能减退症合并胆汁淤积时氢化可的松和左甲状腺素的剂量调整
Clin Pediatr Endocrinol. 2006;15(3):93-6. doi: 10.1297/cpe.15.93. Epub 2006 Aug 2.
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Isolated cortisol deficiency: a rare cause of neonatal cholestasis.孤立性皮质醇缺乏症:新生儿胆汁淤积的罕见病因。
Saudi J Gastroenterol. 2012 Sep-Oct;18(5):339-41. doi: 10.4103/1319-3767.101137.
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Liver dysfunction associated with congenital hypopituitarism.
J Endocrinol Invest. 2000 Mar;23(3):215-6. doi: 10.1007/BF03343708.
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Growth of infants with neonatal growth hormone deficiency.患有新生儿生长激素缺乏症的婴儿的生长情况
Arch Dis Child. 1992 Jul;67(7):920-4. doi: 10.1136/adc.67.7.920.