医院内病原体在静脉输液中的增殖。
Multiplication of nosocomial pathogens in intravenous feeding solutions.
作者信息
Gelbart S M, Reinhardt G F, Greenlee H B
出版信息
Appl Microbiol. 1973 Dec;26(6):874-9. doi: 10.1128/am.26.6.874-879.1973.
Abstract
A major problem in total parenteral nutrition is sepsis, particularly that caused by Candida. Studies of four solutions, a casein hydrolysate, a fibrin hydrolysate, and two crystalline amino acid solutions, show that the protein hydrolysate solutions appear to be highly selective for Candida over bacteria, whereas the crystalline amino acid solutions are not. These findings suggest that the crystalline amino acid preparations may offer a partial solution to the infection problem by minimizing the contribution of the solution as a reservoir for organism multiplication, because they retard the growth of both bacteria and Candida.
摘要
全胃肠外营养中的一个主要问题是败血症，尤其是由念珠菌引起的败血症。对四种溶液（一种酪蛋白水解物、一种纤维蛋白水解物和两种结晶氨基酸溶液）的研究表明，蛋白质水解物溶液对念珠菌的选择性似乎高于细菌，而结晶氨基酸溶液则不然。这些发现表明，结晶氨基酸制剂可能通过尽量减少溶液作为微生物繁殖宿主的作用，为感染问题提供部分解决方案，因为它们会抑制细菌和念珠菌的生长。
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本文引用的文献
1
Contamination of intravenous fluids by bacteria and fungi during preparation and administration.
Am J Hosp Pharm. 1971 Oct;28(10):764-7.
2
The growth of Candida albicans in nutritive solutions given parenterally.白色念珠菌在经肠外给予的营养溶液中的生长情况。
Arch Surg. 1971 Dec;103(6):705-8. doi: 10.1001/archsurg.1971.01350120069012.
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First of all do no harm.
N Engl J Med. 1971 Nov 25;285(22):1258-9. doi: 10.1056/NEJM197111252852209.
4
Fungal septicemia in patients receiving parenteral hyperalimentation.接受胃肠外高营养患者的真菌败血症
N Engl J Med. 1971 Nov 25;285(22):1221-5. doi: 10.1056/NEJM197111252852203.
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New horizons for intravenous feeding.静脉营养的新视野。
JAMA. 1971 Feb 8;215(6):939-49.
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Sepsis caused by contaminated intravenous fluids. Epidemiologic, clinical, and laboratory investigation of an outbreak in one hospital.受污染静脉输液引发的脓毒症。一家医院疫情的流行病学、临床及实验室调查。
Ann Intern Med. 1972 Dec;77(6):881-90. doi: 10.7326/0003-4819-77-6-881.
7
Intravenous hyperalimentation without sepsis.无脓毒症的静脉高营养
Surg Gynecol Obstet. 1973 Apr;136(4):577-85.
8
Infection control in total parenteral nutrition.全胃肠外营养中的感染控制
JAMA. 1973 Mar 19;223(12):1360-4.
9
Septicemia and total parenteral nutrition. Distinguishing catheter-related from other septic episodes.
JAMA. 1973 Mar 19;223(12):1341-4.
10
Growth of Candida in casein hydrolysate solutions.
N Engl J Med. 1972 Mar 16;286(11):612-3. doi: 10.1056/NEJM197203162861129.
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