Bartlett J G
Am Rev Respir Dis. 1979 Jan;119(1):19-23. doi: 10.1164/arrd.1979.119.1.19.
Clinical features of 46 patients with anaerobic bacterial pneumonitis were compared with those of patients with pneumococcal pneumonia. The presenting features in these 2 groups were comparable in terms of fever, leukocyte count, and radiographic abnormalities. In only 2 patients with anaerobic bacterial pneumonitis was putrid sputum noted on initial evaluation. None of the patients with anaerobic bacterial pneumonitis had shaking chills, although this was reported by nearly one half of those with pneumococcal pneumonia. The response to treatment with antimicrobial drugs was comparable in the 2 groups, except that 20% of patients with anaerobic bacterial pneumonitis subsequently developed pulmonary abscesses, despite the use of antimicrobial agents presumed to be active against the infecting flora. There was also a high incidence of bronchogenic neoplasms among patients who had anaerobic bacterial pneumonitis in the absence of an associated condition that would predispose to aspiration. The findings of this review suggest that anaerobic bacterial pneumonitis may be difficult to distinguish from pneumococcal pneumonia on the basis of clinical presentation.
对46例厌氧细菌性肺炎患者的临床特征与肺炎球菌肺炎患者的临床特征进行了比较。这两组患者在发热、白细胞计数和影像学异常方面的表现特征具有可比性。在最初评估时,仅2例厌氧细菌性肺炎患者咳出恶臭痰液。厌氧细菌性肺炎患者均无寒战,而近一半的肺炎球菌肺炎患者有寒战报告。两组对抗菌药物治疗的反应具有可比性,但20%的厌氧细菌性肺炎患者尽管使用了据推测对感染菌群有效的抗菌药物,随后仍发生了肺脓肿。在无易致误吸相关疾病的厌氧细菌性肺炎患者中,支气管源性肿瘤的发生率也很高。本综述的结果表明,基于临床表现,厌氧细菌性肺炎可能难以与肺炎球菌肺炎相区分。