Gayou R, Rudolph R
Ann Plast Surg. 1979 Jan;2(1):62-71. doi: 10.1097/00000637-197901000-00011.
Contraction of fibrous capsules is the most common complication of augmentation mammaplasty using silicone implants. This contraction occurs unpredictably with all kinds of implants, and despite various surgical maneuvers to prevent it. Current clinical practices are reviewed. Wound healing around silicone breast implants is similar to that elsewhere in the body. Acute inflammation is followed by collagen synthesis. Breast capsules contain contractile fibroblasts like those found in other contracting scars. Silicones implanted into tissue undergo some detectable changes that at present cannot be related to capsular contraction. The possible roles of physical and chemical characteristics of the silicone implants are discussed. Steroids are widely used to prevent contraction, but much debate exists over whether or not they actually work. Other possible drug treatments are discussed, based on current research.
纤维包膜挛缩是使用硅胶植入物进行隆乳术最常见的并发症。无论使用何种类型的植入物，这种挛缩都会不可预测地发生，尽管采取了各种外科手术操作来预防它。本文对当前的临床实践进行了综述。硅胶乳房植入物周围的伤口愈合与身体其他部位相似。急性炎症之后是胶原蛋白合成。乳房包膜含有与其他收缩性瘢痕中发现的类似的收缩性成纤维细胞。植入组织中的硅胶会发生一些可检测到的变化，目前这些变化与包膜挛缩无关。讨论了硅胶植入物的物理和化学特性可能发挥的作用。类固醇被广泛用于预防挛缩，但对于它们是否真的有效存在很多争议。基于当前的研究，还讨论了其他可能的药物治疗方法。
