运输上皮细胞的行为。I. 一个基本模型的计算机分析。
The behaviour of transporting epithelial cells. I. Computer analysis of a basic model.
作者信息
Lew V L, Ferreira H G, Moura T
出版信息
Proc R Soc Lond B Biol Sci. 1979 Nov 30;206(1162):53-83. doi: 10.1098/rspb.1979.0091.
PMID:42070
Abstract
We analyse the non-steady state behaviour of a computer model representing functional epithelial cells. The results show that a simple model of an epithelium, containing the essential ion transport asymmetries of the original Koefoed-Johnsen-Ussing model, predicts much of the observed behaviour of 'tight-type' epithelia under various well characterized experimental conditions.
摘要
我们分析了一个代表功能性上皮细胞的计算机模型的非稳态行为。结果表明，一个包含原始科弗德 - 约翰森 - 乌辛模型基本离子转运不对称性的简单上皮模型，在各种特征明确的实验条件下，能够预测“紧密型”上皮细胞的许多观察到的行为。
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