Kiloh L G, Gye R S, Rushworth R G, Bell D S, White R T
J Neurol Neurosurg Psychiatry. 1974 Apr;37(4):437-44. doi: 10.1136/jnnp.37.4.437.
Amygdaloidotomy was performed bilaterally on 15 and unilaterally on three patients exhibiting severe aggressive or self-mutilating behaviour. Nine subjects (50%) were improved a year after operation; improvement was maintained in seven (39%) for periods ranging from 27 months to nearly six years. Four non-epileptic cases had convulsions during the period of review; one of them has a persistent mild hemiparesis dating from the postoperative period. There was a tendency for epileptics to respond better than non-epileptics and for mentally retarded patients to respond poorly, but none of the differences was statistically significant.
对15例表现出严重攻击或自残行为的患者双侧进行了杏仁核切开术,对3例患者单侧进行了该手术。9名受试者(50%)术后一年有所改善;7名(39%)患者的改善持续了27个月至近6年不等。在随访期间,4例非癫痫患者出现惊厥;其中1例自术后起持续存在轻度偏瘫。癫痫患者的反应倾向于比非癫痫患者更好,智力迟钝患者的反应较差,但这些差异均无统计学意义。