促甲状腺激素释放激素：在大鼠脑中的区域分布
Thyrotropin-releasing hormone: regional distribution in rat brain.
作者信息
Winokur A, Utiger R D
出版信息
Science. 1974 Jul 19;185(4147):265-7. doi: 10.1126/science.185.4147.265.
PMID:4209271
Abstract
A sensitive and specific radioimmnunoassay has been used to measure the distribution of thyrotropin-releasing hormone (TRH) in rat brain. All areas of brain tested, except cerebellum, contained readily measurable amounts of TRH. The hypothalamus contained only 31.2 percent of the total brain content of TRH. These results support recent suggestions of central actions for TRH in addition to its hypophysiotropic functions.
摘要
一种灵敏且特异的放射免疫分析法已被用于测定促甲状腺激素释放激素（TRH）在大鼠脑中的分布。除小脑外，所检测的脑的所有区域都含有易于测量的TRH量。下丘脑所含的TRH仅占脑内TRH总量的31.2%。这些结果支持了近期有关TRH除了其促垂体功能外还具有中枢作用的观点。
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