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[高压高氧环境下人体血浆中的红细胞生成抑制剂]

[Plasma erythropoiesis inhibitors in humans during hyperbaric hyperoxia].

作者信息

Voĭtkevich V I, Volzhskaia A M, Korchinskiĭ L A

出版信息

Biull Eksp Biol Med. 1979 Feb;87(2):122-3.

PMID:420929
Abstract

Before exposure of man to hyperbaric hyperoxia the blood plasma possessed marked erythropoietic activity. Erythropoietins disappeared completely and erythropoiesis inhibitors appeared in the plasma of persons untrained to hyperbaric hyperoxia after a 24-hour exposure to hyperoxic conditions (25% of oxygen in the inhaled air) in the high pressure chamber corresponding to the depth of 63 metres. A reduction of the peripheral red blood indices was observed by that time.

摘要

在人体暴露于高压高氧环境之前,血浆具有显著的促红细胞生成活性。在高压舱内对应63米深度的高氧条件(吸入空气中氧气含量为25%)下暴露24小时后,未经高压高氧训练的人的血浆中促红细胞生成素完全消失,且出现了促红细胞生成抑制剂。此时观察到外周血红细胞指标下降。

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