[西格列汀对大鼠血液和肝脏中甘油三酯及胆固醇浓度的影响]
[Effect of sigetin on the concentration of triglycerides and cholesterol in rat blood and liver].
作者信息
Svergun V T
出版信息
Biull Eksp Biol Med. 1979 Feb;87(2):151-3.
PMID:420935
Abstract
It was shown in experiments on male rats that sygethin an analogue of synesterol devoid of estrogenic effect decreased cholesterol level in the intact animals and diminished hypercholesterolemia induced by dexamethasone. Sygethin inhibited the hypertriglyceridemia induced by diethylstilbestrol, as well as by ethanol and dexamethasone.
摘要
在对雄性大鼠进行的实验中发现，孕甾二烯醇（一种无雌激素作用的孕甾醇类似物）可降低正常动物的胆固醇水平，并减轻地塞米松诱导的高胆固醇血症。孕甾二烯醇可抑制己烯雌酚、乙醇和地塞米松诱导的高甘油三酯血症。
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