Pasquier B, Pasquier D, Lachard A, N'Golet A, Panh M H, Couderc P
Bull Cancer. 1979;66(1):25-8.
Extraneural metastases of central nervous system tumours are very rare (248 of histologically proven examples in the literature). They are mainly in adult males and in the following descending order of frequency: gliomas (39.5%), meningeal tumours and sarcomas (28.2%), neuronal tumours (14.1%), lymphomas-microgliomas (12.5%), pineal tumours (4%) and melanomas (1.6%); 10 cases out of 248 developed through a shunt. 19 were observed without any surgical operation. There are still many uncertainties about their pathogenesis. It seems however that in some tumours the increased survival time and the repetition of the craniotomy favorises the metastasis.
中枢神经系统肿瘤的神经外转移非常罕见(文献中经组织学证实的病例有248例)。主要发生在成年男性中,按频率由高到低依次为:胶质瘤(39.5%)、脑膜肿瘤和肉瘤(28.2%)、神经肿瘤(14.1%)、淋巴瘤-小胶质细胞瘤(12.5%)、松果体肿瘤(4%)和黑色素瘤(1.6%);248例中有10例是通过分流装置发生转移的。19例是在未进行任何手术的情况下观察到的。关于它们的发病机制仍有许多不确定因素。然而,似乎在某些肿瘤中,生存时间的延长和开颅手术的重复会促进转移。