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从虱中肠细胞到粪便的普氏立克次体的超微结构研究:寻找“休眠”形式。

Ultrastructural studies of Rickettsia prowazeki from louse midgut cells to feces: search for "dormant" forms.

作者信息

Silverman D J, Boese J L, Wisseman C L

出版信息

Infect Immun. 1974 Jul;10(1):257-63. doi: 10.1128/iai.10.1.257-263.1974.

DOI:10.1128/iai.10.1.257-263.1974
PMID:4210339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC414986/
Abstract

An electron microscope study of infected human louse gut cells and feces was made to determine whether a valid correlation exists between the increased resistance of Rickettsia prowazeki (in the louse feces) to adverse environmental influences and changes in the organism which might be reflected in its ultrastructure. Upon fine structural examination of this intracellular parasite as it passed from the louse midgut cell to the feces, it was apparent that no such morphological changes had occurred.

摘要

对受感染的人体虱子肠道细胞和粪便进行了电子显微镜研究,以确定普氏立克次体(在虱子粪便中)对不利环境影响的抵抗力增强与该生物体可能反映在其超微结构中的变化之间是否存在有效关联。在对这种细胞内寄生虫从虱子中肠细胞到粪便的过程进行精细结构检查时,很明显没有发生这种形态变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/2299330c9c35/iai00247-0275-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/f52addf7284d/iai00247-0272-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/d6f0f838d882/iai00247-0273-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/42d9c6c90cd1/iai00247-0273-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/0d3c98db1d5d/iai00247-0274-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/2299330c9c35/iai00247-0275-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/f52addf7284d/iai00247-0272-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/d6f0f838d882/iai00247-0273-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/42d9c6c90cd1/iai00247-0273-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/0d3c98db1d5d/iai00247-0274-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/991f/414986/2299330c9c35/iai00247-0275-a.jpg

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本文引用的文献

1
The influence of certain salts, amino acids, sugars, and proteins on the stability of rickettsiae.某些盐类、氨基酸、糖类及蛋白质对立克次氏体稳定性的影响。
J Bacteriol. 1950 Apr;59(4):509-22. doi: 10.1128/jb.59.4.509-522.1950.
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Metabolic studies of rickettsiae. I. The effects of antimicrobial substances and enzyme inhibitors on the oxidation of glutamate by purified rickettsiae.立克次氏体的代谢研究。I. 抗菌物质和酶抑制剂对纯化立克次氏体氧化谷氨酸的影响。
J Immunol. 1951 Aug;67(2):123-36.
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The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.
立克次氏体与宿主细胞相互作用的体外研究:普氏立克次氏体感染鸡胚成纤维细胞的超微结构研究
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Ultrastructural study of ehrlichial organisms in the large colons of ponies infected with Potomac horse fever.感染波托马克马热的小马大结肠中埃里希氏体的超微结构研究
Infect Immun. 1985 Sep;49(3):505-12. doi: 10.1128/iai.49.3.505-512.1985.
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In vitro studies on Rickettsia-host cell interactions: lag phase in intracellular growth cycle as a function of stage of growth of infecting Rickettsia prowazeki, with preliminary observations on inhibition of rickettsial uptake by host cell fragments.立克次氏体与宿主细胞相互作用的体外研究:细胞内生长周期中的延迟期与感染的普氏立克次氏体生长阶段的关系,以及关于宿主细胞碎片抑制立克次氏体摄取的初步观察。
Infect Immun. 1976 Jun;13(6):1749-60. doi: 10.1128/iai.13.6.1749-1760.1976.
6
External layers of Rickettsia prowazekii and Rickettsia rickettsii: occurrence of a slime layer.普氏立克次体和立氏立克次体的外层:黏液层的存在
Infect Immun. 1978 Oct;22(1):233-46. doi: 10.1128/iai.22.1.233-246.1978.
在电子显微镜检查中,将高pH值的柠檬酸铅用作电子不透明染色剂。
J Cell Biol. 1963 Apr;17(1):208-12. doi: 10.1083/jcb.17.1.208.
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Improvements in epoxy resin embedding methods.环氧树脂包埋方法的改进。
J Biophys Biochem Cytol. 1961 Feb;9(2):409-14. doi: 10.1083/jcb.9.2.409.
5
[Biological properties of Rickettsia mooseri following prolonged cultivation in the intestine of body louse. III. Electron microscopy of morphological aspects of Rickettsia mooseri and prowazekii].鼠型斑疹伤寒立克次体在体虱肠道中长期培养后的生物学特性。III. 鼠型斑疹伤寒立克次体和普氏立克次体形态学方面的电子显微镜观察
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[Changes in concepts on the epidemiology of epidemic typhus during the last fifty years].[过去五十年来流行性斑疹伤寒流行病学概念的变化]
Schweiz Z Pathol Bakteriol. 1953;16(5):802-20.
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[Structural organization of Rickettsia].[立克次氏体的结构组织]
Vestn Akad Med Nauk SSSR. 1969;24(10):35-40.
8
Purification of large quantities of coxiella burnetii rickettsia by density gradient zonal centrifugation.通过密度梯度区带离心法纯化大量伯纳特柯克斯体立克次氏体。
Appl Microbiol. 1972 May;23(5):1015-22. doi: 10.1128/am.23.5.1015-1022.1972.
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Isolation and characterization of two cell types of Coxiella burneti phase I.伯氏考克斯氏体I期两种细胞类型的分离与鉴定
J Bacteriol. 1972 Apr;110(1):368-77. doi: 10.1128/jb.110.1.368-377.1972.
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Inhibition of haemaggregation by lepromin and other mycobacterial substances.麻风菌素及其他分枝杆菌物质对血细胞凝集的抑制作用。
Nature. 1967 Dec 9;216(5119):1019-20. doi: 10.1038/2161019a0.