Chandra R K
Br Med J. 1974 Sep 7;3(5931):608-9. doi: 10.1136/bmj.3.5931.608.
The frequency of rosette-forming thymus-dependent lymphocytes was reduced in the peripheral blood of malnourished infants and children. The reduced frequency parallelled the impairment of delayed hypersensitivity response to 2, 4-dinitrochlorobenzene and decreased DNA synthesis by lymphocytes challenged with phytohaemagglutinin. The abnormalities were reversed on nutritional improvement.
营养不良婴幼儿外周血中形成玫瑰花结的胸腺依赖性淋巴细胞频率降低。频率降低与对2,4 -二硝基氯苯的迟发型超敏反应受损以及用植物血凝素刺激的淋巴细胞DNA合成减少平行。营养状况改善后,这些异常情况得到逆转。