• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Decreased half life of cyclophosphamide in patients under continual treatment.

作者信息

D'Incalci M, Bolis G, Facchinetti T, Mangioni C, Morasca L, Morazzoni P, Salmona M

出版信息

Eur J Cancer (1965). 1979 Jan;15(1):7-10. doi: 10.1016/0014-2964(79)90198-1.

DOI:10.1016/0014-2964(79)90198-1
PMID:421718
Abstract
摘要

相似文献

1
Decreased half life of cyclophosphamide in patients under continual treatment.持续治疗患者中，环磷酰胺的半衰期缩短。
Eur J Cancer (1965). 1979 Jan;15(1):7-10. doi: 10.1016/0014-2964(79)90198-1.
2
Pharmacokinetics of cyclophosphamide after prolonged low dose treatment in ovarian cancer patients.卵巢癌患者长期低剂量治疗后环磷酰胺的药代动力学
Eur J Drug Metab Pharmacokinet. 1979;4(2):83-5. doi: 10.1007/BF03189405.
3
Metabolism of anticancer agents in man.抗癌药物在人体内的代谢。
Ann N Y Acad Sci. 1971 Jul 6;179:432-41. doi: 10.1111/j.1749-6632.1971.tb46920.x.
4
Intermittent high-dose cyclophosphamide (NSC-26271) treatment of stage III ovarian carcinoma.
Cancer Chemother Rep. 1974 Sep-Oct;58(5 Pt 1):697-703.
5
Pharmacokinetics of cyclophosphamide and alkylating activity in man after intravenous and oral administration.静脉注射和口服后环磷酰胺在人体中的药代动力学及烷化活性
Br J Clin Pharmacol. 1979 Sep;8(3):209-17. doi: 10.1111/j.1365-2125.1979.tb01004.x.
6
The biotransformation of cyclophosphamide in man: analysis of the variation in normal subjects.环磷酰胺在人体内的生物转化：正常受试者的变异分析。
Acta Pharmacol Toxicol (Copenh). 1974 Aug;35(2):98-106. doi: 10.1111/j.1600-0773.1974.tb00729.x.
7
Decreased plasma half-life of cyclophosphamide during repeated high-dose administration.
Cancer Chemother Pharmacol. 1983;10(3):192-3. doi: 10.1007/BF00255760.
8
Pharmacokinetics of intraperitoneal doxorubicin in combination with systemic cyclophosphamide and cis-platinum in the treatment of stage III ovarian cancer.腹腔内注射阿霉素联合全身应用环磷酰胺和顺铂治疗Ⅲ期卵巢癌的药代动力学
Gynecol Oncol. 1990 Feb;36(2):185-8. doi: 10.1016/0090-8258(90)90170-p.
9
Disposition of cyclophosphamide on two consecutive cycles of treatment in patients with ovarian carcinoma.卵巢癌患者连续两个治疗周期中环磷酰胺的处置情况。
Arzneimittelforschung. 1988 Jun;38(6):839-42.
10
Clinical pharmacology of cyclophosphamide.环磷酰胺的临床药理学
Cancer Res. 1973 Feb;33(2):226-33.

引用本文的文献

1
Phase I and clinical pharmacology study of bevacizumab, sorafenib, and low-dose cyclophosphamide in children and young adults with refractory/recurrent solid tumors.贝伐珠单抗、索拉非尼和低剂量环磷酰胺治疗儿童和青年难治/复发性实体瘤的 I 期和临床药理学研究。
Clin Cancer Res. 2013 Jan 1;19(1):236-46. doi: 10.1158/1078-0432.CCR-12-1897. Epub 2012 Nov 8.
2
Clinical pharmacokinetics of cyclophosphamide.环磷酰胺的临床药代动力学
Clin Pharmacokinet. 2005;44(11):1135-64. doi: 10.2165/00003088-200544110-00003.
3
New insights into the pharmacokinetics and metabolism of (R,S)-ifosfamide in cancer patients using a population pharmacokinetic-metabolism model.
Pharm Res. 2000 Jun;17(6):645-52. doi: 10.1023/a:1007561727948.
4
Metabolism and pharmacokinetics of oxazaphosphorines.恶唑磷类化合物的代谢与药代动力学
Clin Pharmacokinet. 2000 Apr;38(4):291-304. doi: 10.2165/00003088-200038040-00001.
5
Ifosfamide clinical pharmacokinetics.异环磷酰胺的临床药代动力学。
Clin Pharmacokinet. 1994 Jun;26(6):439-56. doi: 10.2165/00003088-199426060-00003.
6
The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion.
Cancer Chemother Pharmacol. 1995;36(1):53-60. doi: 10.1007/BF00685732.
7
Cyclophosphamide and dimethylsulfoxide in the treatment of squamous carcinoma of the lung. Therapeutic efficacy, toxicity, and pharmacokinetics.环磷酰胺与二甲基亚砜治疗肺鳞状细胞癌。治疗效果、毒性及药代动力学。
Cancer Chemother Pharmacol. 1981;6(2):117-20. doi: 10.1007/BF00262327.
8
Decreased plasma half-life of cyclophosphamide during repeated high-dose administration.
Cancer Chemother Pharmacol. 1983;10(3):192-3. doi: 10.1007/BF00255760.
9
Bioavailability of cyclophosphamide from oral formulations.口服制剂中环磷酰胺的生物利用度。
Eur J Clin Pharmacol. 1984;26(2):269-70. doi: 10.1007/BF00630298.
10
Pharmacokinetics of high-dose cyclophosphamide in patients with metastatic bronchogenic carcinoma.高剂量环磷酰胺在转移性支气管癌患者中的药代动力学
Cancer Chemother Pharmacol. 1983;11(3):196-9. doi: 10.1007/BF00254204.