Pauwels R, Bazin H, Platteau B, Van Der Straeten M
Int Arch Allergy Appl Immunol. 1979;58(3):351-7. doi: 10.1159/000232212.
Five different rat strains were immunized with 100 microgram ovalbumin and 1 mg Al (OH)3. A good correlation was found between the total serum IgE level of a rat strain before immunization and the IgE antibody production. Good IgE antibody-producing strains had high total serum IgE levels and vice versa. A discordance between the evolution of the total serum IgE level after immunization and the changes in IgE antibody level was found in all strains.
用100微克卵清蛋白和1毫克氢氧化铝对五种不同的大鼠品系进行免疫。发现大鼠品系免疫前的血清总IgE水平与IgE抗体产生之间存在良好的相关性。产生良好IgE抗体的品系血清总IgE水平较高,反之亦然。在所有品系中均发现免疫后血清总IgE水平的变化与IgE抗体水平的变化不一致。