年龄对大鼠IgE产生的影响。
The effect of age on IgE production in rats.
作者信息
Pauwels R, Bazin H, Platteau B, van der Straeten M
出版信息
Immunology. 1979 Jan;36(1):145-9.
Abstract
Inbred BN-rats were immunized at different ages with a standardized amount of ovalbumin and a1(OH)3. The specific IgE antibody response and total serum IgE levels were significantly influenced by age. The IgE antibody response increased to a maximum in 2-month-old rats and decreased progressively at a more advanced age. Total serum IgE levels increased progressively from the age of 1 month to the age of 5 months and decreased again at the age of one year.
摘要
用标准化剂量的卵清蛋白和α1(OH)3在不同年龄对近交系BN大鼠进行免疫。年龄对特异性IgE抗体反应和血清总IgE水平有显著影响。IgE抗体反应在2月龄大鼠中增加到最大值，并在更高龄时逐渐降低。血清总IgE水平从1月龄到5月龄逐渐升高，在1岁时再次下降。
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