Bennett N B, Ogston C M, McAndrew G M, Ogston D
J Clin Pathol. 1966 May;19(3):241-3. doi: 10.1136/jcp.19.3.241.
Plasma fibrinolytic activity, inhibitors of fibrinolysis, and fibrinogen were estimated in 34 subjects of varying ratio of observed to standard weight. The inverse relationship between fibrinolytic activity and the ratio of observed to standard weight was confirmed. No significant correlation was found between anti-plasmin or anti-urokinase and the ratio of observed to standard weight. It was therefore concluded that the decreased plasma fibrinolytic activity in obese subjects is due to decreased production of plasminogen activator rather than to excessive inhibition.
对34名实际体重与标准体重比例各异的受试者的血浆纤溶活性、纤溶抑制物和纤维蛋白原进行了评估。纤溶活性与实际体重和标准体重之比之间的负相关关系得到了证实。未发现抗纤溶酶或抗尿激酶与实际体重和标准体重之比之间存在显著相关性。因此得出结论，肥胖受试者血浆纤溶活性降低是由于纤溶酶原激活物生成减少而非抑制过度所致。
