Grice H C, Zawidzka Z Z, Beare J L
Can J Comp Med Vet Sci. 1966 Feb;30(2):42-6.
The hematologic response in various animal species fed cholesterol and fat differed with the species and sex. Male rabbits, chickens and guinea pigs could not adequately comensate for the demand for increased red cell production and developed anemia. Female guinea pigs given added cholesterol and fat maintained adequate blood cell production but may have become anemic if the test period had been extended. Bone marrow production was increased in male rats and was sufficient to compensate for red cell loss. Blood and bone marrow values were not altered in female chickens by the dietary treatment. Fatty changes in the liver were common to all species fed added cholesterol and fat but gastric lesions were seen only in the rabbit.
给不同动物物种喂食胆固醇和脂肪后，其血液学反应因物种和性别而异。雄性兔子、鸡和豚鼠无法充分补偿红细胞生成增加的需求，从而出现贫血。添加胆固醇和脂肪的雌性豚鼠能维持足够的血细胞生成，但如果试验期延长，可能会出现贫血。雄性大鼠的骨髓生成增加，足以补偿红细胞的损失。饮食处理未改变雌性鸡的血液和骨髓指标。喂食添加胆固醇和脂肪的所有物种肝脏均出现脂肪变化，但只有兔子出现胃部病变。
