表皮细胞优先黏附于IV型（基底膜）胶原蛋白。
Epidermal cells adhere preferentially to type IV (basement membrane) collagen.
作者信息
Murray J C, Stingl G, Kleinman H K, Martin G R, Katz S I
出版信息
J Cell Biol. 1979 Jan;80(1):197-202. doi: 10.1083/jcb.80.1.197.
Abstract
Epidermal cells from adult guinea pig skin attach and differentiate preferentially on substrates of type IV (basement membrane) collagen, compared to those of types I--III collagen. In contrast, guinea pig dermal fibroblasts attach equally well to all four collagen substrates. Fibronectin mediates the attachment of fibroblasts but not of epidermal cells to collagen.
摘要
与I - III型胶原蛋白相比，成年豚鼠皮肤的表皮细胞优先附着并分化于IV型（基底膜）胶原蛋白底物上。相比之下，豚鼠真皮成纤维细胞对所有四种胶原蛋白底物的附着情况相同。纤连蛋白介导成纤维细胞而非表皮细胞与胶原蛋白的附着。
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