皮肤基底膜中胶原成分的定位
Localization of the collagenous component in skin basement membrane.
作者信息
Yaoita H, Foidart J M, Katz S I
出版信息
J Invest Dermatol. 1978 Apr;70(4):191-3. doi: 10.1111/1523-1747.ep12541313.
PMID:347005
Abstract
Antibodies to type IV collagen were produced by immunizing rabbits with a basement membrane collagen obtained from a transplantable mouse tumor. Using specifically purified antibodies, type IV collagen was localized ultrastructurally to the basal lamina part of the basement membrane zone.
摘要
通过用从可移植小鼠肿瘤中获得的基底膜胶原蛋白免疫兔子，产生了针对IV型胶原蛋白的抗体。使用特异性纯化的抗体，IV型胶原蛋白在超微结构上定位于基底膜区的基底层部分。
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