Ohno K, Enomoto T, Imamoto J, Takeshita K, Arima M
J Comput Assist Tomogr. 1979 Feb;3(1):92-5. doi: 10.1097/00004728-197902000-00015.
Unusual computed tomographic findings were observed in two infants with similar clinical pictures including delay in developmental milestones, seizures, decerebrated posture, and microcephaly. Computed tomography revealed small brain with widened subarachnoid space, smooth surface of the brain, uniformly enlarged ventricles, wide sylvian cisterns, and lack of insular opercularization. These findings coincide with pathologic features of lissencephaly (agyria), a rare congenital anomaly of the brain due to interruption of neuronal migration.
在两名临床表现相似的婴儿中观察到异常的计算机断层扫描结果,这些表现包括发育里程碑延迟、癫痫发作、去大脑强直姿势和小头畸形。计算机断层扫描显示脑体积小,蛛网膜下腔增宽,脑表面光滑,脑室均匀扩大,大脑外侧裂池增宽,岛盖缺如。这些发现与无脑回畸形(脑回缺失)的病理特征相符,无脑回畸形是一种由于神经元迁移中断导致的罕见先天性脑异常。