Byrd S E, Osborn R E, Bohan T P, Naidich T P
Department of Radiology, Children's Memorial Hospital, Northweastern University Medical School, Chicago, Illinois.
Pediatr Radiol. 1989;19(3):151-6. doi: 10.1007/BF02388643.
The migrational disorders are a rare group of congenital malformations of the brain. They consist of the following entities--lissencephaly (agyria-pachygyria), pachygyria, schizencephaly, heterotopia and polymicrogyria. We studied 40 children with migrational disorders radiologically with CT and MR. This article (part I) deals with our patients their characteristic CT and MR findings along with their clinical presentation and course. These patients presented with one or a combination of the following symptoms, hypotonia, seizures, failure to thrive, microcephaly and occasionally hydrocephalus. These two groups of migrational disorders have abnormalities affecting the gyral-sulcal pattern of the cortex and gray-white matter distribution of the brain. MR provided better delineation of these disorders than CT. Because some forms of the migrational disorders can be inherited, it is extremely important for the radiologist to understand the characteristic findings for correct diagnosis which is essential for parental counseling.
移行障碍是一组罕见的先天性脑畸形。它们包括以下几种类型——无脑回畸形（无脑回-巨脑回畸形）、巨脑回畸形、脑裂畸形、异位症和多小脑回畸形。我们对40例患有移行障碍的儿童进行了CT和MR影像学研究。本文（第一部分）介绍了我们的患者、他们典型的CT和MR表现以及临床表现和病程。这些患者出现以下一种或多种症状：肌张力减退、癫痫发作、发育不良、小头畸形，偶尔还会出现脑积水。这两组移行障碍都有影响大脑皮质脑回-脑沟模式和灰白质分布的异常。MR对这些疾病的显示比CT更好。由于某些类型的移行障碍可能是遗传性的，放射科医生了解其特征性表现以进行正确诊断非常重要，这对为家长提供咨询至关重要。
