Evans C A, Mattern K L
J Invest Dermatol. 1979 Feb;72(2):103-6. doi: 10.1111/1523-1747.ep12530309.
Although Propionibacterium acnes ordinarily grows as an anaerobe, this organism was commonly seen on aerobic primary cultures (directly from skin) of the forehead, axilla, deltoid area, and antecubital fossa. On subculture, strains from aerobic primary cultures showed their normal anaerobic state. On repeated tests of the foreheads of 7 subjects over periods of 1 to 4 yr, 24% of all cultures were positive for propionibacteria (P. acnes) on aerobic culture. This phenomenon was equally common in cultures from those with relatively sparse or dense populations of P. acnes on the skin surface. Several different patterns of aerobic growth were observed: satellitism, profuse growth at one dilution and none on the next higher dilution, and proportionate growth in successive dilutions. These different growth patterns indicate that more than one mechanism is operative in stimulating the aerobic growth of propionibacteria. Whether one or more of these mechanisms is operative in vivo, we do not know, but it appears that they do not account for the great individual differences in population density of P. acnes on such sites as the forehead.
虽然痤疮丙酸杆菌通常作为厌氧菌生长，但在额头、腋窝、三角肌区域和肘前窝的需氧原代培养物（直接取自皮肤）中常见到这种微生物。在传代培养时，需氧原代培养物中的菌株呈现出其正常的厌氧状态。在对7名受试者的额头进行为期1至4年的重复检测中，所有培养物中有24%在需氧培养时痤疮丙酸杆菌呈阳性。这种现象在皮肤表面痤疮丙酸杆菌数量相对稀少或密集的人群的培养物中同样常见。观察到几种不同的需氧生长模式：卫星现象、在一种稀释度下大量生长而在下一个更高稀释度下不生长，以及在连续稀释中按比例生长。这些不同的生长模式表明，不止一种机制在刺激痤疮丙酸杆菌的需氧生长。我们不知道这些机制中的一种或多种在体内是否起作用，但似乎它们并不能解释额头等部位痤疮丙酸杆菌种群密度的巨大个体差异。
