Mann J E, Sperelakis N
J Electrocardiol. 1979 Jan;12(1):23-33. doi: 10.1016/s0022-0736(79)80041-2.
We previously described a model for the electrical transfer of excitation from one cell to the next which utilized the electric field generated in the cleft between the cells. This model was analyzed only for the steady-state condition. In the present paper, we calculate the effects of membrane capacitance on the transmission of an action potential between two adjacent cardiac cells; the junction between cells was composed of two high-resistance excitable membranes separated by a narrow cleft. The parameters varied for this study included the threshold potential and capacitance of the junctional membranes. The calculations indicate that it is somewhat easier to achieve transmission when capacitive effects are included. Thus, the electric field model provides an alternative means of cell-to-cell propagation between myocardial cells which is electrical in nature but does not require the presence of low-resistance connections between cells.
我们之前描述了一种用于将兴奋从一个细胞电传递到下一个细胞的模型，该模型利用了细胞间裂隙中产生的电场。该模型仅针对稳态条件进行了分析。在本文中，我们计算了膜电容对两个相邻心肌细胞之间动作电位传导的影响；细胞间连接由两个高电阻可兴奋膜组成，中间隔着一个狭窄的裂隙。本研究中变化的参数包括连接膜的阈值电位和电容。计算结果表明，当考虑电容效应时，实现传导会稍微容易一些。因此，电场模型提供了一种心肌细胞间细胞间传播的替代方式，其本质上是电的，但不需要细胞间存在低电阻连接。
