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The potential in the gap between two abutting cardiac muscle cells. A closed solution.两个相邻心肌细胞之间间隙中的电位。一种封闭解。
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本文引用的文献

1
A quantitative description of membrane current and its application to conduction and excitation in nerve.膜电流的定量描述及其在神经传导和兴奋中的应用。
J Physiol. 1952 Aug;117(4):500-44. doi: 10.1113/jphysiol.1952.sp004764.
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The diffusion of radiopotassium across intercalated disks of mammalian cardiac muscle.放射性钾在哺乳动物心肌闰盘间的扩散。
J Physiol. 1966 Nov;187(2):323-42. doi: 10.1113/jphysiol.1966.sp008092.
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Electrical transmission at the nexus between smooth muscle cells.平滑肌细胞之间连接部位的电传导。
J Gen Physiol. 1968 Mar;51(3):347-68. doi: 10.1085/jgp.51.3.347.
4
The potential in the gap between two abutting cardiac muscle cells. A closed solution.两个相邻心肌细胞之间间隙中的电位。一种封闭解。
Biophys J. 1970 Nov;10(11):1076-83. doi: 10.1016/S0006-3495(70)86353-6.
5
Applications of Hodgkin-Huxley equations to excitable tissues.
Physiol Rev. 1966 Jan;46(1):1-50. doi: 10.1152/physrev.1966.46.1.1.

心脏细胞电相互作用的模拟。

Simulation of electrical interaction of cardiac cells.

作者信息

Heppner D B, Plonsey R

出版信息

Biophys J. 1970 Nov;10(11):1057-75. doi: 10.1016/S0006-3495(70)86352-4.

DOI:10.1016/S0006-3495(70)86352-4
PMID:5471697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1367982/
Abstract

A model of the electrical activity of excitable membrane was used to simulate action potential propagation in cardiac cells. Using an implicit method for solving finite difference equations, propagation through the intercalated disc region between two abutting cells was studied. A model of interaction was constructed and parameters of the cellular junction determined. Estimates of the intercalated disc resistance were then made from these junction parameters using a field analysis of the junction. Values of approximately 4 Omega-cm(2) were found and correlate well with experimentally measured values.

摘要

利用可兴奋膜电活动模型模拟心脏细胞动作电位的传播。采用隐式方法求解有限差分方程，研究了动作电位在两个相邻细胞间闰盘区域的传播。构建了相互作用模型并确定了细胞连接的参数。然后利用连接的场分析从这些连接参数估计闰盘电阻。得到的值约为4Ω·cm²，与实验测量值相关性良好。