Bicyclic pyrazolines, potential central nervous system depressants and antiinflammatory agents.
作者信息
Krapcho J, Turk C F
出版信息
J Med Chem. 1979 Feb;22(2):207-10. doi: 10.1021/jm00188a018.
PMID:423202
Abstract
The synthesis and CNS activity of a series of 34 substituted bicyclic pyrazolines are described. Ten of these compounds were also screened for antiinflammatory activity. One of the compounds (15) exhibited significant antiinflammatory activity in the carrageenan-induced edema test.
摘要
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