双环吡唑啉类化合物，潜在的中枢神经系统抑制剂和抗炎剂。
Bicyclic pyrazolines, potential central nervous system depressants and antiinflammatory agents.
作者信息
Krapcho J, Turk C F
出版信息
J Med Chem. 1979 Feb;22(2):207-10. doi: 10.1021/jm00188a018.
PMID:423202
Abstract
The synthesis and CNS activity of a series of 34 substituted bicyclic pyrazolines are described. Ten of these compounds were also screened for antiinflammatory activity. One of the compounds (15) exhibited significant antiinflammatory activity in the carrageenan-induced edema test.
摘要
描述了一系列34种取代双环吡唑啉的合成及其对中枢神经系统的活性。还对其中10种化合物进行了抗炎活性筛选。其中一种化合物（15）在角叉菜胶诱导的水肿试验中表现出显著的抗炎活性。
Zotero 插件