7-氧代-1H,7H-吡唑并[1,5-a]嘧啶-6-N-吡啶基羧酰胺的合成与抗炎活性
Synthesis and antiinflammatory activity of 7-oxo-1H,7H-pyrazolo[1,5-a]pyrimidine-6-N-pyridylcarboxamides.
作者信息
Doria G, Passarotti C, Sala R, Magrini R, Sberze P, Tibolla M, Buttinoni A, Ferrari M, Tremolada L
出版信息
Farmaco Sci. 1985 Nov;40(11):808-17.
PMID:4085643
Abstract
A series of 7-oxo-1H,7H-pyrazolo[1,5-a]pyrimidine-6-N-pyridylcarboxamides was synthesized and assayed in the carrageenin-induced paw oedema test in the rat. Some compounds showed moderate antiinflammatory activity.
摘要
合成了一系列7-氧代-1H，7H-吡唑并[1,5-a]嘧啶-6-N-吡啶基羧酰胺，并在大鼠角叉菜胶诱导的爪肿胀试验中进行了测定。一些化合物表现出中等程度的抗炎活性。
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