氧化甾醇去甲基化的组成反应研究。反对细胞色素P-450参与的证据。 - Suppr

Suppr

超能文献

Investigation of the component reactions of oxidative sterol demethylation. Evidence against participation of cytochrome P-450.

作者信息

Gaylor J L, Mason H S

出版信息

J Biol Chem. 1968 Oct 10;243(19):4966-72.

PMID:4234469

Abstract

摘要

相似文献

Investigation of the component reactions of oxidative sterol demethylation. Evidence against participation of cytochrome P-450.氧化甾醇去甲基化的组成反应研究。反对细胞色素P-450参与的证据。

J Biol Chem. 1968 Oct 10;243(19):4966-72.

Dual effect of ethyl isocyanide on drug hydroxylation by liver microsomes.

J Biochem. 1968 Mar;63(3):380-9.

The selective stimulation, inhibition, and physicochemical alteration of the 7- and 16-alpha-hydroxylases of 3-beta-hydroxyandrost-5-en-17-one and drug-metabolizing enzymes in hepatic microsomal fractions.3-β-羟基雄甾-5-烯-17-酮的7-α和16-α羟化酶以及肝微粒体部分中药物代谢酶的选择性刺激、抑制和物理化学改变。

Biochemistry. 1968 Jun;7(6):2273-80. doi: 10.1021/bi00846a033.

Investigation of the component reactions of oxidative sterol demethylation. Formation and metabolism of 3-ketosteroid intermediates.氧化甾醇脱甲基化的组成反应研究。3-酮甾体中间体的形成与代谢。

J Biol Chem. 1968 Nov 10;243(21):5546-55.

Behavior of two states of the ethyl isocyanide compound of reduced P-450 in oxidation-reduction cycle.

J Biochem. 1968 Mar;63(3):370-9.

Microsomal cytochromes b5 and P450 during induction of aryl hydrocarbon hydroxylase activity in mammalian cell culture.哺乳动物细胞培养中芳烃羟化酶活性诱导过程中的微粒体细胞色素b5和P450

J Biol Chem. 1970 Feb 10;245(3):519-27.

On the properties of the 12 alpha-hydroxylase in cholic acid biosynthesis. Bile acids and steroids. 198.关于胆酸生物合成中12α-羟化酶的性质。胆汁酸与类固醇。198

Eur J Biochem. 1968 Jun;5(1):101-8. doi: 10.1111/j.1432-1033.1968.tb00342.x.

The intracellular organisation of cholesterol biosynthesis. A review.

Steroids Lipids Res. 1972;3(4):236-56.

Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation.

Biochem Biophys Res Commun. 1969 Aug 15;36(4):545-51. doi: 10.1016/0006-291x(69)90339-8.

A soluble 2,3-oxidosqualene sterol cyclase.一种可溶性2,3-氧化角鲨烯甾醇环化酶。

J Biol Chem. 1967 Jun 25;242(12):3014-5.

引用本文的文献

Human hepatic metabolism of the anti-osteoporosis drug eldecalcitol involves sterol C4-methyl oxidase.人肝脏代谢抗骨质疏松药物艾地骨化醇涉及固醇 C4-甲基氧化酶。

Pharmacol Res Perspect. 2015 Mar;3(2):e00120. doi: 10.1002/prp2.120. Epub 2015 Feb 10.

Microsomal enzymes of cholesterol biosynthesis from lanosterol: a progress report.从羊毛甾醇合成胆固醇的微粒体酶：进展报告。

Lipids. 1982 Mar;17(3):250-6. doi: 10.1007/BF02535112.

Some properties of the microsomal 2,3-oxidosqualene sterol cyclase.微粒体2,3-氧化角鲨烯甾醇环化酶的一些特性。

Proc Natl Acad Sci U S A. 1969 May;63(1):110-7. doi: 10.1073/pnas.63.1.110.

Cytochrome P-450 in steroid biogenesis.细胞色素P - 450在类固醇生物合成中的作用。

Biochem J. 1969 Dec;115(5):24P-25P. doi: 10.1042/bj1150024p.

Sphingolipids and their precursors in human brain (normal and MS).人脑中的鞘脂及其前体（正常和多发性硬化症）。

Z Neurol. 1972;202(2):104-20. doi: 10.1007/BF00316160.

Effects of ketoconazole on cholesterol synthesis and precursor concentrations in the rat liver.酮康唑对大鼠肝脏胆固醇合成及前体浓度的影响。

Lipids. 1987 Dec;22(12):1020-4. doi: 10.1007/BF02536443.

The mechanism of C-20 hydroxylation of alpha-ecdysone in the desert locust, Schistocerca gregaria.沙漠蝗（Schistocerca gregaria）中α-蜕皮激素C-20羟基化的机制。

Biochem J. 1977 Dec 15;168(3):513-20. doi: 10.1042/bj1680513.

The effects of halothane on hepatic microsomal electron transfer.氟烷对肝微粒体电子传递的影响。

Biochem J. 1975 May;148(2):179-86. doi: 10.1042/bj1480179.

Regulation of microsomal stearoyl-coenzyme A desaturase. Purification of a non-substrate-binding protein that stimulates activity.微粒体硬脂酰辅酶A去饱和酶的调节。一种刺激活性的非底物结合蛋白的纯化。

Biochem J. 1979 Nov 1;183(2):405-15. doi: 10.1042/bj1830405.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验