增殖性皮肤病猪皮肤的组织病理学变化。

Percy D H, Hulland T J

Can J Comp Med. 1969 Jan;33(1):48-54.

Dermatosis vegetans, an hereditary disease seen in Landrace swine, is characterized by defects in the skin, and a giant cell pneumonia. Histological changes of the skin from 12 affected pigs of various ages were described. Lesions of the skin were characterized by acanthosis, hyperkeratosis, parakeratosis, and leukocytic infiltration. In general, the defects followed a definite developmental pattern, which were divided into three stages: (1) the stage of early development, (2) the intermediate stage characterized by an acute inflammatory response, and (3) the stage of regression. The specific role of the eosinophil, a prominent feature in this and other diseases of the porcine skin, remains obscure.

增殖性皮肤病是大白猪中出现的一种遗传性疾病，其特征为皮肤缺陷和巨细胞性肺炎。描述了12头不同年龄患病猪皮肤的组织学变化。皮肤病变的特征为棘层肥厚、角化过度、不全角化和白细胞浸润。一般来说，这些缺陷遵循一定的发育模式，分为三个阶段：（1）早期发育阶段，（2）以急性炎症反应为特征的中间阶段，（3）消退阶段。嗜酸性粒细胞在这种以及猪皮肤的其他疾病中是一个突出特征，但其具体作用仍不清楚。