Sloman G, Duffield A, Hunt D, Mond H, Hobbs J
Med J Aust. 1979 Jan 27;1(2):39-43.
Mitral valve prolapse is a relatively common condition in the general population. The syndrome appears more common in females, and is often associated with a family history. Patients may be asymptomatic or may present with a variety of symptoms ranging from mild chest aches and anxiety to severe angina-like chest pain, palpitations and dizziness. The common auscultatory features include mid-systolic clicks and a late systolic murmur, either alone or in combination. The wide spectrum of symptoms and signs may be explained by ventriculovalvular disproportion, where either the ventricle is too small for the valve, or the valve is too large for the ventricle. The long-term prognosis is very good; severe mitral regurgitation can occasionally develop, but both sudden death and bacterial endocarditis are rare. No treatment is required for asymptomatic patients, beyond antibiotic cover for dental procedures and surgery.
二尖瓣脱垂在普通人群中是一种相对常见的病症。该综合征在女性中似乎更为常见,且常与家族病史相关。患者可能无症状,或可能出现多种症状,从轻微的胸痛和焦虑到严重的心绞痛样胸痛、心悸和头晕。常见的听诊特征包括收缩中期喀喇音和收缩晚期杂音,可单独出现或同时出现。症状和体征的广泛表现可能由心室瓣膜比例失调来解释,即要么心室相对于瓣膜过小,要么瓣膜相对于心室过大。长期预后非常好;偶尔会发展为严重的二尖瓣反流,但猝死和细菌性心内膜炎都很罕见。无症状患者除了在牙科手术和外科手术时给予抗生素预防外,无需其他治疗。