Dorfman S G, Dillaplain R P, Gambrell R D
Obstet Gynecol. 1979 Mar;53(3 Suppl):21S-24S.
Antepartum pituitary infarction occurs only in insulin-dependent diabetic patients. It is manifested by severe headache, followed by decreasing insulin requirements. Delivery is frequently premature, with high fetal wastage and increased maternal mortality. During the puerperium, the first manifestation of pituitary deficiency, other than a lower insulin requirement than would be expected, is failure to lactate. Subsequent evaluation of pituitary function reveals variable deficiencies with loss of growth hormone and gonadotropins being most frequent. This case is the eighth report of this entity, and it represents the first patient to survive a pituitary infarction prior to the third trimester of pregnancy. Recognition of this syndrome is critical in order to ensure that the mother's health and the viability of the offspring be preserved.
产前垂体梗死仅发生于胰岛素依赖型糖尿病患者。其表现为严重头痛，随后胰岛素需求量减少。分娩往往早产，胎儿死亡率高，产妇死亡率增加。在产褥期，垂体功能减退的首发表现，除了胰岛素需求量低于预期外，是乳汁分泌不足。随后对垂体功能的评估显示存在多种功能减退，其中生长激素和促性腺激素缺乏最为常见。该病例是此病症的第八例报告，也是妊娠晚期前垂体梗死存活的首例患者。认识到这种综合征对于确保母亲的健康和后代的存活至关重要。
