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[杏仁核破坏与刺激对幼鼠卵巢和子宫对氢化可的松及脱氧皮质酮敏感性的影响]

[Effect of destruction and stimulation of the amygdaloid nuclei on the sensitivity of the ovaries and uterus of infantile rats to hydrocortisone and desoxycorticosterone].

作者信息

Malitsa N A

出版信息

Probl Endokrinol (Mosk). 1979 Mar-Apr;25(2):45-50.

PMID:424391
Abstract

The effect of destruction and stimulation of the amygdaloid nuclei on the sensitivity of the ovaries and uterus to hydrocortisone and deoxycorticosterone was studied in 190 infantile female albino rats. Administration of the hormones following the action upon the amygdaloid nuclei led to a sharp reduction of the weight of the ovaries and uterus, an increase in the count of compact and vesicular follicles with reduction of their size. Adrenalectomy with the following destruction and stimulation of the amygdaloid nuclei and the hormone administration led to an even greater reduction in weight of the ovaries; as to the count and size of compact and vesicular follicles--it decreased, and the uterus gained weight.

摘要

在190只幼年雌性白化大鼠中研究了杏仁核破坏和刺激对卵巢和子宫对氢化可的松和脱氧皮质酮敏感性的影响。在对杏仁核施加作用后给予激素,导致卵巢和子宫重量急剧减轻,致密卵泡和囊状卵泡数量增加,但其大小减小。在进行肾上腺切除术后,对杏仁核进行破坏和刺激并给予激素,导致卵巢重量进一步大幅减轻;至于致密卵泡和囊状卵泡的数量和大小——其数量减少,子宫重量增加。

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