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克林霉素的临床与细菌学研究。

Clinical and bacteriological studies with clindamycin.

作者信息

Geddes A M, Bridgwater F A, Williams D N, Oon J, Grimshaw G J

出版信息

Br Med J. 1970 Jun 20;2(5711):703-4. doi: 10.1136/bmj.2.5711.703.

DOI:10.1136/bmj.2.5711.703
PMID:4246870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1700701/
Abstract

Fifty patients have been treated with clindamycin, a chemical analogue of lincomycin. Forty-four responded satisfactorily to treatment. Gastrointestinal side-effects were rare though five patients developed rashes. Most recently isolated staphylococci are clindamycin-sensitive.

摘要

五十名患者接受了克林霉素治疗,克林霉素是林可霉素的化学类似物。四十四名患者对治疗反应良好。胃肠道副作用很少见,不过有五名患者出现了皮疹。最近分离出的葡萄球菌对克林霉素敏感。

相似文献

1
Clinical and bacteriological studies with clindamycin.克林霉素的临床与细菌学研究。
Br Med J. 1970 Jun 20;2(5711):703-4. doi: 10.1136/bmj.2.5711.703.
2
Treatment of penicillin-resistant staphylococcal infections with clindamycin.用克林霉素治疗耐青霉素葡萄球菌感染。
Am J Med Sci. 1971 Apr;261(4):207-12. doi: 10.1097/00000441-197104000-00004.
3
Lincomycin and clindamycin.林可霉素和克林霉素。
Br J Dermatol. 1970 Nov;83(5):604-6. doi: 10.1111/j.1365-2133.1970.tb15752.x.
4
[Laboratory and clinical evaluation of clindamycin].
Jpn J Antibiot. 1971 Apr;24(2):51-8.
5
[Experience in the use of lincomycin in the treatment of staphylococcal infections in traumatologic and orthopedic patients].
Antibiotiki. 1969 Sep;14(9):858-61.
6
Bacteriological assessment of clindamycin, a new lincomycin derivative.新型林可霉素衍生物克林霉素的细菌学评估
J Med Microbiol. 1971 Nov;4(4):529-34. doi: 10.1099/00222615-4-4-529.
7
Clinical and laboratory experience with clindamycin.克林霉素的临床及实验室经验
Antimicrob Agents Chemother (Bethesda). 1970;10:481-5.
8
[Clinical evaluation of clindamycin (7-chlorolincomycin) in the urological field].[克林霉素(7-氯林可霉素)在泌尿外科领域的临床评估]
Jpn J Antibiot. 1971 Apr;24(2):59-63.
9
The treatment of paediatric infections with the lincomycins.林可霉素类药物治疗小儿感染
Br J Clin Pract. 1973 Aug;27(8):315-8.
10
Lincomycin and clindamycin in the treatment of infections of the hand.林可霉素与克林霉素治疗手部感染
Practitioner. 1972 Dec;209(254):787-93.

引用本文的文献

1
Immediate and Delayed Hypersensitivity Reactions to Antibiotics: Aminoglycosides, Clindamycin, Linezolid, and Metronidazole.抗生素的即刻和迟发性过敏反应:氨基糖苷类、克林霉素、利奈唑胺和甲硝唑。
Clin Rev Allergy Immunol. 2022 Jun;62(3):463-475. doi: 10.1007/s12016-021-08878-x. Epub 2021 Dec 15.
2
HLA-B*51:01 is strongly associated with clindamycin-related cutaneous adverse drug reactions.HLA - B*51:01与克林霉素相关的皮肤药物不良反应密切相关。
Pharmacogenomics J. 2017 Dec;17(6):501-505. doi: 10.1038/tpj.2016.61. Epub 2016 Aug 16.
3
Hypersensitivity reactions to non beta-lactam antimicrobial agents, a statement of the WAO special committee on drug allergy.世界变态反应组织药物过敏特别委员会关于非β-内酰胺类抗菌药物过敏反应的声明。
World Allergy Organ J. 2013 Oct 31;6(1):18. doi: 10.1186/1939-4551-6-18.
4
[Not Available].[无可用内容]。
Can Fam Physician. 1972 Feb;18(2):134-6.
5
Identification of adverse reactions to new drugs. II (continued): How were 18 important adverse reactions discovered and with what delays?新药不良反应的识别。II(续):18种重要不良反应是如何被发现的,以及延迟了多久?
Br Med J (Clin Res Ed). 1983 Jan 29;286(6362):365-8. doi: 10.1136/bmj.286.6362.365.
6
Clindamycin levels in sputum in a patient with purulent chest disease due to cystic fibrosis.一名因囊性纤维化导致化脓性胸部疾病患者痰液中的克林霉素水平。
Postgrad Med J. 1971 Jun;47(548):366-7. doi: 10.1136/pgmj.47.548.366.
7
Lincomycins in the treatment of bacteroides infections.林可霉素治疗拟杆菌感染
Br Med J. 1972 Jan 29;1(5795):280-2. doi: 10.1136/bmj.1.5795.280.
8
Clinical uses and control of rifampicin and clindamycin.利福平与克林霉素的临床应用及控制
J Clin Pathol. 1971 Jul;24(5):410-8. doi: 10.1136/jcp.24.5.410.
9
Parenteral and oral clindamycin therapy in surgical infections: a preliminary report.手术感染中静脉注射与口服克林霉素治疗:初步报告
Ann Surg. 1973 Nov;178(5):637-42. doi: 10.1097/00000658-197311000-00014.
10
Treatment of severe bacteroides infections with parenteral clindamycin.用胃肠外途径给予克林霉素治疗严重拟杆菌感染。
Can Med Assoc J. 1972 Dec 23;107(12):1177-81.

本文引用的文献

1
Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin.
Am J Med Sci. 1968 Nov;256(5):279-92. doi: 10.1097/00000441-196811000-00002.
2
Drug rash with ampicillin and other penicillins.
Lancet. 1969 Nov 8;2(7628):969-72. doi: 10.1016/s0140-6736(69)90535-2.