氚标记胸腺嘧啶核苷的辐射会干扰受刺激淋巴细胞的细胞周期进程。
Radiation from tritiated thymidine perturbs the cell cycle progression of stimulated lymphocytes.
作者信息
Pollack A, Bagwell C B, Irvin G L
出版信息
Science. 1979 Mar 9;203(4384):1025-7. doi: 10.1126/science.424727.
PMID:424727
Abstract
Tritiated thymidine was found to affect the cell cycle progression of phytohemagglutinin-stimulated human lymphocytes. By means of flow cytometry a statistically significant increase in the G2 and M phases of the cell cycle was observed in cultures with low concentrations of tritiated thymidine added 18 hours before the cultures were harvested.
摘要
发现氚标记的胸腺嘧啶核苷会影响植物血凝素刺激的人淋巴细胞的细胞周期进程。通过流式细胞术观察到，在收获培养物前18小时添加低浓度氚标记胸腺嘧啶核苷的培养物中，细胞周期的G2期和M期有统计学意义的增加。
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