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暗饲猫的外侧膝状体核:Y细胞缺失但细胞大小无变化。

Lateral geniculate nucleus in dark-reared cats: loss of Y cells without changes in cell size.

作者信息

Kratz K E, Sherman S M, Kalil R

出版信息

Science. 1979 Mar 30;203(4387):1353-5. doi: 10.1126/science.424758.

DOI:10.1126/science.424758
PMID:424758
Abstract

In cats reared in the dark from birth until 4 months of age, the dorsal lateral geniculate nucleus contained few normal Y cells in either the binocular or monocular segments. Although most of the neurons appeared to be normal X cells unaffected by light deprivation, many cells with abnormal receptive field and response charcteristics were encountered. These effects were permanent, since 1 to 2 years of normal visual experience following initial light deprivation did not lead to any functional recovery. The sizes of cell bodies in cats reared in the dark were similar to those of normal animals, an indication that changes in geniculate cell physiology need not be related to changes in cell size.

摘要

在从出生到4个月大一直饲养在黑暗中的猫中,无论是双眼段还是单眼段,背外侧膝状核中正常的Y细胞都很少。虽然大多数神经元似乎是正常的X细胞,未受光剥夺的影响,但仍发现许多具有异常感受野和反应特征的细胞。这些影响是永久性的,因为在最初的光剥夺之后1至2年的正常视觉经验并未导致任何功能恢复。在黑暗中饲养的猫的细胞体大小与正常动物的相似,这表明膝状体细胞生理学的变化不一定与细胞大小的变化有关。

相似文献

1
Lateral geniculate nucleus in dark-reared cats: loss of Y cells without changes in cell size.暗饲猫的外侧膝状体核:Y细胞缺失但细胞大小无变化。
Science. 1979 Mar 30;203(4387):1353-5. doi: 10.1126/science.424758.
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Monocular deprivation: morphological effects on different classes of neurons in the lateral geniculate nucleus.单眼剥夺:对视外侧膝状体核不同类型神经元的形态学影响。
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引用本文的文献

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Development of Functional Properties in the Early Visual System: New Appreciations of the Roles of Lateral Geniculate Nucleus.早期视觉系统功能特性的发展:对外侧膝状体作用的新认识。
Curr Top Behav Neurosci. 2022;53:3-35. doi: 10.1007/7854_2021_297.
2
Recovery of neurofilament following early monocular deprivation.早期单眼剥夺后的神经丝恢复。
Front Syst Neurosci. 2012 Apr 9;6:22. doi: 10.3389/fnsys.2012.00022. eCollection 2012.
3
Vision triggers an experience-dependent sensitive period at the retinogeniculate synapse.视觉在视网膜神经节突触处引发一个依赖于经验的敏感期。
J Neurosci. 2008 Apr 30;28(18):4807-17. doi: 10.1523/JNEUROSCI.4667-07.2008.
4
Is there an effect of monocular deprivation on the proportions of X and Y cells in the cat lateral geniculate nucleus?单眼剥夺对猫外侧膝状核中X细胞和Y细胞的比例有影响吗?
Exp Brain Res. 1980;39(1):41-8. doi: 10.1007/BF00237068.
5
Spatial and temporal properties of cat geniculate neurones after prolonged deprivation.长期剥夺后猫膝状神经元的时空特性
J Physiol. 1981 May;314:107-20. doi: 10.1113/jphysiol.1981.sp013694.
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Critical flicker fusion in Siamese cats.暹罗猫的临界闪烁融合
Exp Brain Res. 1981;43(1):65-8. doi: 10.1007/BF00238810.
7
Effects of monocular deprivation on the lateral geniculate nucleus in a primate.单眼剥夺对灵长类动物外侧膝状体核的影响。
Proc Natl Acad Sci U S A. 1984 Apr;81(7):2255-9. doi: 10.1073/pnas.81.7.2255.
8
The structure of the terminal arborizations of physiologically identified retinal ganglion cell Y axons in the kitten.小猫体内经生理鉴定的视网膜神经节细胞Y轴突终末分支的结构。
J Physiol. 1985 Feb;359:293-313. doi: 10.1113/jphysiol.1985.sp015586.
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The role of visual experience in the development of cat striate cortex.视觉经验在猫纹状皮层发育中的作用。
Cell Mol Neurobiol. 1985 Jun;5(1-2):103-21. doi: 10.1007/BF00711088.
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