长期剥夺后猫膝状神经元的时空特性
Spatial and temporal properties of cat geniculate neurones after prolonged deprivation.
作者信息
Derrington A M, Hawken M J
出版信息
J Physiol. 1981 May;314:107-20. doi: 10.1113/jphysiol.1981.sp013694.
Abstract
- Extracellular recordings were made from the dorsal lateral geniculate nucleus of monocularly deprived, dark-reared and normal cats. The spatial and temporal properties of the neurones were studied. 2. The mean acuity of X-cells with receptive fields 3 degrees of the area centralis was 3.9 c/degree for deprived eye cells from monocularly deprived cats, compared was 3.8 c/degree for normal cells. 3. The mean activity of X-cells with receptive fields within 4 degrees of the area centralis was 4.3 c/degree for a dark-reared cat compared with 4.0 c/degree for a normal cat. 4. The peak response rates of X-cells to their best spatial frequency were determined. The mean values for the normal, monocularly deprived and dark-reared populations were all similar. 5 Measurement of the temporal frequency tuning of a number of cells was made. The mean peak temporal frequency for the dark-reared X-cells was lower than for monocularly deprived or normal X-cells. 6. The results are discussed with reference to the location of the primary neural deficit induced by visual deprivation.
摘要
- 对单眼剥夺、黑暗饲养和正常猫的背外侧膝状核进行细胞外记录。研究了神经元的空间和时间特性。2. 对于单眼剥夺猫的剥夺眼细胞，其感受野在中央凹区域3度范围内的X细胞的平均视敏度为3.9周/度，而正常细胞为3.8周/度。3. 对于黑暗饲养的猫，其感受野在中央凹区域4度范围内的X细胞的平均活性为4.3周/度，而正常猫为4.0周/度。4. 确定了X细胞对其最佳空间频率的峰值反应率。正常、单眼剥夺和黑暗饲养群体的平均值都相似。5. 对一些细胞的时间频率调谐进行了测量。黑暗饲养的X细胞的平均峰值时间频率低于单眼剥夺或正常的X细胞。6. 参照视觉剥夺引起的主要神经缺陷的位置对结果进行了讨论。
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