• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Glycolytic enzymes in adipose tissue of adult diabetics.成年糖尿病患者脂肪组织中的糖酵解酶
Br Med J. 1970 Aug 22;3(5720):444-5. doi: 10.1136/bmj.3.5720.444.
2
Glycolytic enzymes in human adipose tissue of diabetics.
Clin Sci. 1971 Feb;40(2):3P. doi: 10.1042/cs040003p.
3
The effect of starvation and diabetes on glycolytic enzymes in human adipose tissue.
Clin Sci. 1971 Dec;41(6):545-53. doi: 10.1042/cs0410545.
4
[Enzymatic aspects of the adipose tissue and hepatic tissue in obese subjects and in diabetics].
Minerva Med. 1979 May 12;70(23):1671-80.
5
Effects of diabetes on glucose metabolism in human adipose tissue.
Horm Metab Res. 1970;2:Suppl 2:172-4.
6
The effect of obesity and Cushing's disease on the incorporation of glucose into lipid and esterification of palmitate by human adipose tissue.肥胖和库欣病对人体脂肪组织中葡萄糖掺入脂质及棕榈酸酯酯化作用的影响。
Eur J Clin Invest. 1972 Nov;2(6):379-83. doi: 10.1111/j.1365-2362.1972.tb00665.x.
7
The effects of exercise and dietary restriction on the activities of hexokinase and phosphofructokinase in superficial, intra-abdominal and intermuscular adipose tissue of guinea-pigs.
Comp Biochem Physiol B. 1987;87(3):533-42. doi: 10.1016/0305-0491(87)90049-6.
8
Comparative aspects of hexokinase and phosphofructokinase activity in intermuscular adipose tissue.
Comp Biochem Physiol B. 1987;87(3):543-51. doi: 10.1016/0305-0491(87)90050-2.
9
Effects of vitamin B6 deficiency on liver, kidney, and adipose tissue enzymes associated with carbohydrate and lipid metabolism, and on glucose uptake by rat epididymal adipose tissue.维生素B6缺乏对与碳水化合物和脂质代谢相关的肝脏、肾脏及脂肪组织酶的影响,以及对大鼠附睾脂肪组织葡萄糖摄取的影响。
J Nutr. 1977 Mar;107(3):443-52. doi: 10.1093/jn/107.3.443.
10
Effect of alloxan diabetes, starvation and refeeding on glycolytic kinase activities in rat epididymal adipose tissue.四氧嘧啶糖尿病、饥饿及再喂养对大鼠附睾脂肪组织中糖酵解激酶活性的影响。
Nature. 1967 Oct 14;216(5111):156-7. doi: 10.1038/216156a0.

引用本文的文献

1
Increased lipid synthesis by liver slice in a superfusion system following raised glucose or insulin concentration.
Diabetologia. 1972 Aug;8(4):267-73. doi: 10.1007/BF01225570.
2
Insulin-independent diabetes: a defect in the activity of lipoprotein lipase in adipose tissue.非胰岛素依赖型糖尿病:脂肪组织中脂蛋白脂肪酶活性的缺陷。
Diabetologia. 1979 May;16(5):313-7. doi: 10.1007/BF01223620.

本文引用的文献

1
Effect of alloxan-diabetes on multiple forms of hexokinase in adipose tissue and lung.醛糖糖尿病对脂肪组织和肺中多种形式己糖激酶的影响。
Biochem J. 1967 Dec;105(3):1301-5. doi: 10.1042/bj1051301.
2
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
3
New type of needle for obtaining large samples of human adipose tissue.
J Lipid Res. 1967 Jan;8(1):58-60.
4
THE EFFECT OF INSULIN ON HUMAN ADIPOSE TISSUE.胰岛素对人体脂肪组织的作用。
Can J Biochem. 1964 Nov;42:1623-35. doi: 10.1139/o64-173.
5
ENZYME PATTERNS IN HUMAN TISSUES. II. GLYCOLYTIC ENZYME PATTERNS IN NONMALIGNANT HUMAN TISSUES.人体组织中的酶模式。II. 非恶性人体组织中的糖酵解酶模式。
Cancer Res. 1964 May;24:722-31.
6
Insulin-resistant diabetes associated with increased endogenous plasma insulin followed by complete remission.胰岛素抵抗性糖尿病与内源性血浆胰岛素升高相关,随后完全缓解。
J Clin Invest. 1961 Sep;40(9):1672-83. doi: 10.1172/JCI104390.
7
The effect of diabetes and insulin in vivo and in vitro on a low Km form of hexokinase from various rat tissues.
Biochem Biophys Res Commun. 1966 Aug 23;24(4):531-6. doi: 10.1016/0006-291x(66)90352-4.
8
Defect in glucose utilization in adipose tissue of patients with maturity-onset diabetes.成年型糖尿病患者脂肪组织中葡萄糖利用缺陷。
Br Med J. 1969 Mar 8;1(5644):616-7. doi: 10.1136/bmj.1.5644.616.
9
A defect of glucose utilization in adipose tissue of adult diabetics and in some conditions which may predispose to diabetes.
Clin Sci. 1970 Jun;38(6):661-75. doi: 10.1042/cs0380661.

成年糖尿病患者脂肪组织中的糖酵解酶

Glycolytic enzymes in adipose tissue of adult diabetics.

作者信息

Galton D J, Wilson J P

出版信息

Br Med J. 1970 Aug 22;3(5720):444-5. doi: 10.1136/bmj.3.5720.444.

DOI:10.1136/bmj.3.5720.444
PMID:4247779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1701411/
Abstract

The maximal activities of hexokinase and phosphofructokinase were measured in human adipose tissue. Though the mean activity of hexokinase was similar between a group of adult diabetics (n=24) and a group of non-diabetic controls (n=25), in the diabetic group the activity of phosphofructokinase was definitely reduced. Possibly this enzyme deficiency might contribute to impaired glucose utilization by the adipose cell in diabetes.

摘要

测定了人脂肪组织中己糖激酶和磷酸果糖激酶的最大活性。虽然一组成年糖尿病患者(n = 24)和一组非糖尿病对照组(n = 25)之间己糖激酶的平均活性相似,但糖尿病组中磷酸果糖激酶的活性明显降低。这种酶缺乏可能导致糖尿病患者脂肪细胞对葡萄糖的利用受损。