成年糖尿病患者脂肪组织中的糖酵解酶
Glycolytic enzymes in adipose tissue of adult diabetics.
作者信息
Galton D J, Wilson J P
出版信息
Br Med J. 1970 Aug 22;3(5720):444-5. doi: 10.1136/bmj.3.5720.444.
Abstract
The maximal activities of hexokinase and phosphofructokinase were measured in human adipose tissue. Though the mean activity of hexokinase was similar between a group of adult diabetics (n=24) and a group of non-diabetic controls (n=25), in the diabetic group the activity of phosphofructokinase was definitely reduced. Possibly this enzyme deficiency might contribute to impaired glucose utilization by the adipose cell in diabetes.
摘要
测定了人脂肪组织中己糖激酶和磷酸果糖激酶的最大活性。虽然一组成年糖尿病患者（n = 24）和一组非糖尿病对照组（n = 25）之间己糖激酶的平均活性相似，但糖尿病组中磷酸果糖激酶的活性明显降低。这种酶缺乏可能导致糖尿病患者脂肪细胞对葡萄糖的利用受损。
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