多骨纤维发育不良的恶性转化
Malignant transformation of polyostotic fibrous dysplasia.
作者信息
Johnson C B, Gilbert E F, Gottlieb L I
出版信息
South Med J. 1979 Mar;72(3):353-6. doi: 10.1097/00007611-197903000-00035.
Abstract
We have described an unusual case of polyostotic fibrous dysplasia in a 25-year-old white woman who had malignant transformation into a mesenchymal tumor with widespread metastases and features of rhabdomyosarcoma. Masculinization also occurred with high plasma testosterone levels. A mechanism for the development of masculinizing features is discussed.
摘要
我们描述了一名25岁白人女性的罕见多骨型纤维发育不良病例，该病例发生了恶性转化，形成了具有广泛转移且具有横纹肌肉瘤特征的间充质肿瘤。同时还出现了男性化现象，血浆睾酮水平升高。本文讨论了男性化特征出现的机制。
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