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[骨纤维异常增殖症的恶变。文献病例回顾]

[Malignant transformation of fibrous dysplasia. About a case review of the literature].

作者信息

Bejui-Thivolet F, Patricot L M, Vauzelle J L

出版信息

Sem Hop. 1982 May 27;58(21):1329-35.

PMID:6287591
Abstract

A case of chondrosarcoma arrising from polyostotic form of fibrous dysplasia coming after 35 years is reported. About this new occurence, a review of the 61 cases of the literature is effectuated. Sarcomatous transformation is a rare complication of fibrous dysplasia. Its frequency change with the authors, because of lack of proof of the preexistence of fibrous dysplasia. She occur specially on polyostotic fibrous dysplasia. This complication is severe, death following before two years. In the literature several etiological factors are discussed: repeated X-rays, radioscopic examinations; cartilaginous nodules. In our case we means that the sarcoma arrise on a chondroblastic bone healing.

摘要

报告了1例骨纤维发育异常多骨型35年后发生软骨肉瘤的病例。关于这一新病例,对文献中的61例病例进行了回顾。肉瘤样变是骨纤维发育异常的一种罕见并发症。由于缺乏骨纤维发育异常先前存在的证据,其发生率因作者而异。它特别发生在多骨型骨纤维发育异常中。这种并发症很严重,患者会在两年内死亡。文献中讨论了几种病因:反复的X线检查、透视检查;软骨结节。在我们的病例中,我们认为肉瘤发生于软骨母细胞性骨愈合。

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