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白化大鼠、兔、山羊和绵羊实验性锥虫病的病理学——初步报告

Pathology of experimental trypanosomiasis in the albino rat, rabbit, goat and sheep--A preliminary report.

作者信息

Losos G J, Ikede B O

出版信息

Can J Comp Med. 1970 Jul;34(3):209-12.

PMID:4248442
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1319494/
Abstract

In rats, rabbits, sheep, and goats experimentally infected with several strains of Trypanosoma brucei, the trypanosomes were observed to localise extravascularly in connective tissues. Focal inflammatory reactions were associated with the localisation of the parasites. Trypanosoma congolense in the same species of animals and T. vivax in sheep and goats, were not observed to localise outside blood vessels. On the basis of these observations it appears that the pathogenesis of the disease caused by T. brucei differs from that caused by T. congolense and T. vivax.

摘要

在实验感染了几种布氏锥虫菌株的大鼠、兔子、绵羊和山羊中，观察到锥虫在结缔组织中血管外定位。局部炎症反应与寄生虫的定位有关。在相同动物物种中的刚果锥虫以及绵羊和山羊中的活跃锥虫，未观察到在血管外定位。基于这些观察结果，似乎由布氏锥虫引起的疾病发病机制与由刚果锥虫和活跃锥虫引起的不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/6096feac54b8/compmed00063-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/283256eafadf/compmed00063-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/61bcfc812f9d/compmed00063-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/666522cddc1a/compmed00063-0049-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/7eb0defa9992/compmed00063-0049-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/414056899f80/compmed00063-0049-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/6096feac54b8/compmed00063-0050-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/283256eafadf/compmed00063-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/61bcfc812f9d/compmed00063-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/666522cddc1a/compmed00063-0049-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/7eb0defa9992/compmed00063-0049-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/414056899f80/compmed00063-0049-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bb2/1319494/6096feac54b8/compmed00063-0050-a.jpg

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本文引用的文献

1
CHANGING PATTERNS OF TRYPANOSOMIASIS RESEARCH IN EAST AFRICA.东非锥虫病研究模式的变化
Trans R Soc Trop Med Hyg. 1964 Mar;58:97-135. doi: 10.1016/0035-9203(64)90002-1.
对感染刚果锥虫的兔子进行针对锥虫抗原的抗体介导和细胞介导超敏反应的检测。
Infect Immun. 1972 Jul;6(1):62-7. doi: 10.1128/iai.6.1.62-67.1972.
4
Autoimmunity in experimental Trypanosoma congolense infections of rabbits.兔实验性刚果锥虫感染中的自身免疫
Infect Immun. 1972 May;5(5):648-56. doi: 10.1128/iai.5.5.648-656.1972.
5
Clinical, haematological and pathological studies in donkeys experimentally infected with Trypanosoma brucei.
Trop Anim Health Prod. 1977 May;9(2):93-8. doi: 10.1007/BF02236387.
6
Biologically active products from African Trypanosomes.来自非洲锥虫的生物活性产物。
Microbiol Rev. 1978 Dec;42(4):664-81. doi: 10.1128/mr.42.4.664-681.1978.