Chalifoux A
Can J Comp Med. 1970 Oct;34(4):289-93.
Serum ornithine carbamyl transferase (OCT) was evaluated on eighteen dogs. Three groups were used, the first and second ones were treated with carbon tetrachloride (CCI) to produce acute hepatic necrosis and cirrhosis. To the third group a ductus choledochus ligation was performed to simulate extrahepatic cholestasis. Ornithine carbamyl transferase has proven its use in all phases of hepatic necrosis, but only after the fourth day in the extrahepatic cholestasis. Finally in cirrhosis, it was sometimes difficult to interpret the results.
对18只狗的血清鸟氨酸氨基甲酰转移酶（OCT）进行了评估。实验分为三组，第一组和第二组用四氯化碳（CCI）处理以产生急性肝坏死和肝硬化。对第三组进行胆总管结扎以模拟肝外胆汁淤积。鸟氨酸氨基甲酰转移酶已被证明在肝坏死的各个阶段都有应用，但在肝外胆汁淤积中仅在第四天之后才有作用。最后在肝硬化中，有时难以解释结果。
