Berkowitz F E
S Afr Med J. 1979 Jan 20;55(3):100-1.
A child with facial and digital anomalies and mental retardation after exposure to phenobarbitone during gestation is presented. The teratogenicity of anticonvulsants, including phenobarbitone, is discussed, and guidelines for anticonvulsant therapy during pregnancy are suggested.
本文报告了一名在孕期接触苯巴比妥后出现面部及手指异常和智力发育迟缓的儿童。文中讨论了包括苯巴比妥在内的抗惊厥药物的致畸性,并提出了孕期抗惊厥治疗的指导原则。