一名接受左旋咪唑治疗的关节炎患者发生粒细胞缺乏症。病例报告。
Agranulocytosis in an arthritic patient treated with levamisole. A case report.
作者信息
du P Heyns A, Retief F P, Vorster B J
出版信息
S Afr Med J. 1979 Feb 3;55(5):177-9.
A case of agranulocytosis in a man with nonspecific seronegative polyarthritis treated with levamisole in the form of a proprietary veterinary anthelmintic is described. At the time of presentation he had a relative monocytosis. Recovery was uneventful and was heralded and paralleled by an increase in monocytes, serum vitamin B12 and total vitamin B12 binding capacity. Levamisole induced agranulocytosis and the significance of monocytosis and serum vitamin B12 binding proteins in neutropenia are briefly reviewed.
本文描述了一例患有非特异性血清阴性多关节炎的男性患者，因使用一种专利兽用驱虫药形式的左旋咪唑而发生粒细胞缺乏症。就诊时他存在相对性单核细胞增多。恢复过程顺利，单核细胞、血清维生素B12和总维生素B12结合能力增加预示并伴随了恢复。简要回顾了左旋咪唑诱发的粒细胞缺乏症以及单核细胞增多和血清维生素B12结合蛋白在中性粒细胞减少症中的意义。
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