Cloward R B, Passarelli P
Surg Neurol. 1979 Feb;11(2):129-34.
Chordoma, a primary malignant neoplasm of the cerebro-spinal axis, is difficult to diagnose and impossible to cure. The only effective treatment is early radical surgical removal, regardless of its size or location. A giant, 65gm tumor arising from the clivus, C1 and C2 vertebrae was successfully removed with low morbidity. The surgical technique is described and compared to other operations with their advantages and disadvantages. A plea is made for surgical removal as the initial treatment for these lesions to prevent fatal intracranial metastasis.
脊索瘤是一种发生于脑脊轴的原发性恶性肿瘤，诊断困难且无法治愈。唯一有效的治疗方法是早期根治性手术切除，无论其大小或位置如何。一例重达65克、起源于斜坡、C1和C2椎体的巨大肿瘤被成功切除，且并发症发生率较低。本文描述了该手术技术，并与其他手术的优缺点进行了比较。本文呼吁将手术切除作为这些病变的初始治疗方法，以防止致命的颅内转移。
