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[去神经支配和药物刺激后(可溶于高氯酸的)肌肉糖蛋白]

[Muscle glycoproteins (soluble in perchloric acid) after denervation and drug stimulation].

作者信息

Fedorova L K, Novikova A A

出版信息

Ukr Biokhim Zh (1978). 1979 Jan-Feb;51(1):3-6.

PMID:425135
Abstract

Muscle proteins soluble in perchloric acid contain about 75% of carbohydrates presented by neutral hexoses, fucose and hexuronic acids. Three days and two weeks after denervation the content of the glycoproteids protein part is unchanged, a month later it increases by 116%. The content of carbohydrate component following denervation lowers considerably and a month later is on the average 40% higher than in the muscle of healthy rats. Administration of muscular RNA restores the content of the protein component only by the end of a month; administration of pyrogenal normalizes the content of both protein and carbohydrate components.

摘要

可溶于高氯酸的肌肉蛋白质含有约75%由中性己糖、岩藻糖和己糖醛酸呈现的碳水化合物。去神经支配后三天和两周,糖蛋白的蛋白质部分含量不变,一个月后增加116%。去神经支配后碳水化合物成分的含量大幅降低,一个月后平均比健康大鼠肌肉中的含量高40%。给予肌肉RNA仅在一个月末恢复蛋白质成分的含量;给予热原可使蛋白质和碳水化合物成分的含量均恢复正常。

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