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[个体发育过程中光剥夺后犬脑视觉分析器中的γ-氨基丁酸转氨酶活性]

[GABA-transaminase activity in the dog brain visual analyzer following light deprivation during ontogenesis].

作者信息

Agaev T M

出版信息

Ukr Biokhim Zh (1978). 1979 Jan-Feb;51(1):31-4.

PMID:425136
Abstract

The GABA-transaminase activity is the highest in the subcortical formations of the brain visual analyzer in 45- and 90-day dogs. Deprivation of visual impulses at early stages of postnatal ontogenesis lowers sharply this activity in all the studied areas of the brain visual analyzer. Under conditions of deprivation the content of glutaminic acid increases in all the formations of the dog brain visual analyzer to a considerably less extent, especially in the anterior corpora bigemina and lateral geniculate body at the age of 45- and 90-days. Similar regularities are found in the deprivation effect relative to formation of ascorbic acid the content of which lowers sharply in all the formations of the dog brain visual analyzer on the 90th day of light deprivation.

摘要

在45日龄和90日龄犬的大脑视觉分析器的皮质下结构中,GABA转氨酶活性最高。出生后个体发育早期视觉冲动的剥夺会使大脑视觉分析器所有研究区域的这种活性急剧降低。在剥夺条件下,犬大脑视觉分析器所有结构中的谷氨酸含量均有一定程度的增加,但增加幅度较小,尤其是在45日龄和90日龄时的前二叠体和外侧膝状体。在剥夺对视黄酸形成的影响方面也发现了类似规律,在光照剥夺90天时,犬大脑视觉分析器所有结构中的视黄酸含量均急剧下降。

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