[抗精神病药物锥体外系效应的时间顺序以及黑质纹状体多巴胺能系统]
[Chronology of the extrapyramidal effects of neuroleptics, and the nigrostriatal dopaminergic system].
作者信息
Petit M, Lepine J P, Lesieur P
出版信息
Encephale. 1979;5(4):297-316.
PMID:42527
Abstract
Authors after analysis of the data in literature describe the chronologic appearance of the extrapyramidal effects of neuroleptics. In order to restore a neurophysiological coherence to dissimilar or even contradictory clinical emergences this sequence is analysed in function of the actual data, relative to the mechanism and to the modalities of adaptation of the dopaminergic synapse of the nigro striatal system.
摘要
作者在分析文献中的数据后，描述了抗精神病药物锥体外系效应的时间顺序。为了使不同甚至相互矛盾的临床现象恢复神经生理上的一致性，根据实际数据，从黑质纹状体系统多巴胺能突触的机制和适应方式方面，对这一顺序进行了分析。
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