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Diisopropylammonium dichloroaccetate: regulation of metabolic intermediates in muscle of alloxan diabetic rats.

作者信息

Stacpoole P W, Felts J M

出版信息

Metabolism. 1971 Sep;20(9):830-4. doi: 10.1016/0026-0495(71)90044-8.

DOI:10.1016/0026-0495(71)90044-8
PMID:4254777
Abstract
摘要

相似文献

1
Diisopropylammonium dichloroaccetate: regulation of metabolic intermediates in muscle of alloxan diabetic rats.二异丙胺二氯乙酸盐：对四氧嘧啶糖尿病大鼠肌肉中代谢中间体的调节作用
Metabolism. 1971 Sep;20(9):830-4. doi: 10.1016/0026-0495(71)90044-8.
2
Regulation of glucose uptake by muscles. 10. Effects of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, and of fatty acids, ketone bodies and pyruvate, on the glycerol output and concentrations of free fatty acids, long-chain fatty acyl-coenzyme A, glycerol phosphate and citrate-cycle intermediates in rat heart and diaphragm muscles.肌肉对葡萄糖摄取的调节。10. 四氧嘧啶糖尿病、饥饿、垂体切除和肾上腺切除以及脂肪酸、酮体和丙酮酸对大鼠心脏和膈肌中甘油输出以及游离脂肪酸、长链脂肪酰辅酶A、磷酸甘油和柠檬酸循环中间产物浓度的影响。
Biochem J. 1964 Dec;93(3):678-87. doi: 10.1042/bj0930678.
3
Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles.肌肉对葡萄糖摄取的调节。8. 脂肪酸、酮体和丙酮酸以及四氧嘧啶糖尿病和饥饿对大鼠心脏和膈肌中葡萄糖摄取及代谢归宿的影响。
Biochem J. 1964 Dec;93(3):652-65. doi: 10.1042/bj0930652.
4
The response to ether anesthesia and to electric stimulation of glycolytic metabolites in a red and a white muscle of the rat.大鼠红色和白色肌肉对乙醚麻醉及糖酵解代谢产物电刺激的反应。
Pflugers Arch. 1969;307(3):154-66. doi: 10.1007/BF00592081.
5
Regulation of glucose uptake by muscle. 9. Effects of fatty acids and ketone bodies, and of alloxan-diabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles.肌肉对葡萄糖摄取的调节。9. 脂肪酸、酮体、四氧嘧啶糖尿病和饥饿对大鼠心脏和大鼠膈肌中丙酮酸代谢以及乳酸-丙酮酸和L-甘油3-磷酸-二羟丙酮磷酸浓度比的影响。
Biochem J. 1964 Dec;93(3):665-78. doi: 10.1042/bj0930665.
6
Effects of dichloroacetate on the metabolism of glucose, pyruvate, acetate, 3-hydroxybutyrate and palmitate in rat diaphragm and heart muscle in vitro and on extraction of glucose, lactate, pyruvate and free fatty acids by dog heart in vivo.二氯乙酸对大鼠膈肌和心肌体外葡萄糖、丙酮酸、乙酸、3-羟基丁酸和棕榈酸代谢以及对犬心脏体内葡萄糖、乳酸、丙酮酸和游离脂肪酸摄取的影响。
Biochem J. 1973 Aug;134(4):1067-81. doi: 10.1042/bj1341067.
7
Hormonal regulation of cardiac muscle citrate.
Nature. 1965 Aug 28;207(5000):988-9. doi: 10.1038/207988a0.
8
Diisopropylammonium dichloroacetate (DIPA) and sodium dichloracetate (DCA): effect on glucose and fat metabolism in normal and diabetic tissue.
Metabolism. 1970 Jan;19(1):71-8. doi: 10.1016/0026-0495(70)90119-8.
9
Effect of DL-alpha-lipoic acid on the citrate concentration and phosphofructokinase activity of perfused hearts from normal and diabetic rats.DL-α-硫辛酸对正常及糖尿病大鼠灌流心脏中柠檬酸浓度和磷酸果糖激酶活性的影响。
Biochem Biophys Res Commun. 1970 Nov 9;41(3):555-61. doi: 10.1016/0006-291x(70)90048-3.
10
Measurement of concentrations of metabolites in adipose tissue and effects of insulin, alloxan-diabetes and adrenaline.脂肪组织中代谢物浓度的测量以及胰岛素、四氧嘧啶糖尿病和肾上腺素的影响。
Biochem J. 1966 Aug;100(2):407-19. doi: 10.1042/bj1000407.

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Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.鉴定黑色素瘤免疫治疗的小分子增强剂。
Sci Rep. 2020 Mar 30;10(1):5688. doi: 10.1038/s41598-020-62369-1.
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Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.二氯乙酸的治疗应用及谷胱甘肽转移酶ζ-1的作用
Pharmacol Ther. 2017 Feb;170:166-180. doi: 10.1016/j.pharmthera.2016.10.018. Epub 2016 Oct 19.
3
Activation of pyruvate dehydrogenase in perfused rat heart by dichloroacetate (Short Communication).二氯乙酸对灌流大鼠心脏丙酮酸脱氢酶的激活（简短通讯）。
Biochem J. 1973 Jun;134(2):651-3. doi: 10.1042/bj1340651.
4
Acute effects of dichloroacetate in the depancreatized dog: glucose synthesis and turnover.二氯乙酸对胰腺切除狗的急性影响：葡萄糖合成与周转
Diabetologia. 1982 Jul;23(1):45-8. doi: 10.1007/BF00257730.
5
Effects of dichloroacetate on the metabolism of glucose, pyruvate, acetate, 3-hydroxybutyrate and palmitate in rat diaphragm and heart muscle in vitro and on extraction of glucose, lactate, pyruvate and free fatty acids by dog heart in vivo.二氯乙酸对大鼠膈肌和心肌体外葡萄糖、丙酮酸、乙酸、3-羟基丁酸和棕榈酸代谢以及对犬心脏体内葡萄糖、乳酸、丙酮酸和游离脂肪酸摄取的影响。
Biochem J. 1973 Aug;134(4):1067-81. doi: 10.1042/bj1341067.
6
Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids.二氯乙酸及其他卤代羧酸激活丙酮酸脱氢酶的机制。
Biochem J. 1974 Sep;141(3):761-74. doi: 10.1042/bj1410761.
7
The metabolic effects of sodium dichloroacetate in the starved rat.二氯乙酸钠对饥饿大鼠的代谢影响。
Biochem J. 1974 Aug;142(2):279-86. doi: 10.1042/bj1420279.
8
Inhibition of lactate glucogneogenesis in rat kidney by dichloroacetate.二氯乙酸对大鼠肾脏中乳酸糖异生的抑制作用。
Biochem J. 1978 Mar 15;170(3):551-60. doi: 10.1042/bj1700551.
9
Regulation of mammalian pyruvate dehydrogenase.哺乳动物丙酮酸脱氢酶的调控
Mol Cell Biochem. 1975 Oct 31;9(1):27-53. doi: 10.1007/BF01731731.
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Metabolic interactions of dichloroacetate and insulin in experimental diabetic ketoacidosis.二氯乙酸与胰岛素在实验性糖尿病酮症酸中毒中的代谢相互作用
Biochem J. 1975 Feb;146(2):447-56. doi: 10.1042/bj1460447.