Smith I, Benzie R J, Gordon N L, Kelman G R, Swapp G H
Br Med J. 1971 Aug 14;3(5771):410-1. doi: 10.1136/bmj.3.5771.410.
We have investigated, in 13 artificially ventilated and anaesthetized patients, the cardiovascular effects of peritoneal insufflation of carbon dioxide preparatory to laparoscopy. Stepwise increases of intra-abdominal pressure up to a maximum of 25 cm H(2)O were accompanied by increases of airway pressure, intrathoracic pressure, central venous pressure, and femoral venous pressure and by signs of cardiovascular stimulation with mild tachycardia and hypertension. End-tidal carbon dioxide tension rose only slightly. The anaesthetic technique used provided good surgical conditions; our results suggest that it does not impose undue strain on the homoeostatic ability of the patient's cardiovascular system.
我们对13例人工通气并麻醉的患者进行了研究，观察腹腔镜检查前经腹膜注入二氧化碳对心血管系统的影响。腹腔内压力逐步升高至最高25 cm H₂O，同时气道压力、胸内压、中心静脉压和股静脉压升高，伴有轻度心动过速和高血压等心血管刺激体征。呼气末二氧化碳分压仅略有升高。所采用的麻醉技术提供了良好的手术条件；我们的结果表明，该技术不会给患者心血管系统的稳态调节能力带来过度负担。
