Gyles C L, Stevens J B, Craven J A
Can J Comp Med. 1971 Jul;35(3):258-66.
When 200 Escherichia coli isolated from pigs with gastro-intestinal disease were examined, 82.0% of them were found to be enteropathogenic by the ligated intestine test in pigs. Among the 18.0% which were nonenteropathogenic, 12.0% were obtained from pigs considered likely to be suffering from colibacillosis and 6.0% were from pigs for which there was a satisfactory diagnosis. Eighty-seven percent of the enteropathogens belonged to the serogroups O8:K87;88ac, O116:K"V17";88ac, O147:K89;88ac, O138:K81 and O45:K"E65";88ac. One O4 isolate and two O98 isolates were enteropathogenic, although members of these O groups have not been recognized enteropathogenic types. The majority (153) of the enteropathogens were of the types which are well characterized and which induce fluid accumulation in ligated segments of the intestine of young and old pigs and were referred to as class 1 enteropathogens. A small number (11)were able to cause fluid accumulation in ligated segments of young, but not of older pigs and were referred to as class 2 enteropathogens. Enterotoxin production was demonstrated for strains of all the serogroups of class 1 enteropathogens detected, and transfer of the enterotoxin plasmid was carried out for strains of O groups 4, 45, 98, 116 and 147.
对从患有胃肠道疾病的猪身上分离出的200株大肠杆菌进行检测时，通过猪的肠段结扎试验发现其中82.0%为肠致病性大肠杆菌。在18.0%的非肠致病性大肠杆菌中，12.0%分离自疑似患有大肠杆菌病的猪，6.0%分离自诊断明确的猪。87%的肠致病性大肠杆菌属于O8:K87;88ac、O116:K"V17";88ac、O147:K89;88ac、O138:K81和O45:K"E65";88ac血清群。一株O4分离株和两株O98分离株为肠致病性，尽管这些O群的成员尚未被认定为肠致病性类型。大多数（153株）肠致病性大肠杆菌属于特征明确的类型，可在幼猪和成年猪的肠段结扎部位诱导液体蓄积，被称为1类肠致病性大肠杆菌。少数（11株）能够在幼猪而非成年猪的肠段结扎部位引起液体蓄积，被称为2类肠致病性大肠杆菌。对检测到的所有1类肠致病性大肠杆菌血清群的菌株都进行了肠毒素产生的检测，并对O群4、45、98、116和147的菌株进行了肠毒素质粒的转移试验。
