Hutchins G M, Sheldon W H
Br J Exp Pathol. 1971 Aug;52(4):331-7.
Electrophoretic studies showed that the protein content and composition of inflammatory exudates in cutaneous Arthus reactions of rabbits did not differ quantitatively or qualitatively from controls. The specific antigen always produced positive skin tests. With micro-immunodiffusion specific precipitating antibody was found in most post-immunization sera, but was not demonstrable in the corresponding inflammatory exudates. Inflammation was enhanced in the lesions of Arthus reactions but revealed no distinctive qualitative features. The findings of the present and previous studies suggest that the inflammatory reaction as measured by the protein content and composition of the exudate and by the histology of the cellular responses in skin lesions produced by an immunological stimulus is stereotyped and is only affected quantitatively by the immunological state of the host.
电泳研究表明，兔皮肤阿瑟斯反应中炎性渗出物的蛋白质含量和组成在数量和质量上与对照组并无差异。特异性抗原总能引发阳性皮肤试验。通过微量免疫扩散法发现，大多数免疫后血清中存在特异性沉淀抗体，但在相应的炎性渗出物中未检测到。阿瑟斯反应的病变处炎症增强，但未显示出独特的定性特征。本研究及先前研究的结果表明，由免疫刺激引起的皮肤病变中，通过渗出物的蛋白质含量和组成以及细胞反应的组织学所衡量的炎症反应是定型的，并且仅在数量上受宿主免疫状态的影响。
